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Longistyline C acts antidepressant in vivo and neuroprotection in vitro against glutamate-induced cytotoxicity by regulating NMDAR/NR2B-ERK pathway in PC12 cells
Depressive disorder is a common psychiatric disease which ranks among the leading cause of disability worldwide. The antidepressants presently used had low cure rate and caused a variety of side-effects. The screening of antidepressant drugs is usually used classic behavioural tests and neuroprotect...
Autores principales: | Liu, Yamin, Zhao, Ning, Li, Chenchen, Chang, Qi, Liu, Xinmin, Liao, Yonghong, Pan, Ruile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584824/ https://www.ncbi.nlm.nih.gov/pubmed/28873095 http://dx.doi.org/10.1371/journal.pone.0183702 |
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