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Induction of Mitochondrial Dysfunction and Oxidative Damage by Antibiotic Drug Doxycycline Enhances the Responsiveness of Glioblastoma to Chemotherapy

BACKGROUND: Inducing mitochondrial dysfunction has been recently demonstrated to be an alternative therapeutic strategy for cancer treatment. Doxycycline is an antibiotic that has been shown to have anti-cancer activities in various cancers by way of targeting mitochondria. In this work, we examined...

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Detalles Bibliográficos
Autores principales: Tan, Qian, Yan, Xiaoqiong, Song, Lin, Yi, Hongxiang, Li, Ping, Sun, Guobin, Yu, Danfang, Li, Le, Zeng, Zheng, Guo, Zhenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584825/
https://www.ncbi.nlm.nih.gov/pubmed/28842551
http://dx.doi.org/10.12659/MSM.903245

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