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Cerebrovascular Protective Effect of Boldine Against Neural Apoptosis via Inhibition of Mitochondrial Bax Translocation and Cytochrome C Release

BACKGROUND: In the present study, we explored the protective effect and mechanism of action of boldine (BOL) against neural apoptosis, which is a mediator of TBI. MATERIAL/METHODS: The effect of BOL on mitochondrial and cytosol proteins of extracted from cerebral cortical tissue of mice was evaluate...

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Detalles Bibliográficos
Autores principales: Qiu, Xiaozhong, Shi, Ling, Zhuang, Hanting, Zhang, Hongtao, Wang, Juan, Wang, Lijun, Sun, Peng, Yu, Lili, Liu, Longxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584841/
https://www.ncbi.nlm.nih.gov/pubmed/28841638
http://dx.doi.org/10.12659/MSM.903040