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CRISPR-FOCUS: A web server for designing focused CRISPR screening experiments
The recently developed CRISPR screen technology, based on the CRISPR/Cas9 genome editing system, enables genome-wide interrogation of gene functions in an efficient and cost-effective manner. Although many computational algorithms and web servers have been developed to design single-guide RNAs (sgRN...
Autores principales: | Cao, Qingyi, Ma, Jian, Chen, Chen-Hao, Xu, Han, Chen, Zhi, Li, Wei, Liu, X. Shirley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584922/ https://www.ncbi.nlm.nih.gov/pubmed/28873439 http://dx.doi.org/10.1371/journal.pone.0184281 |
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