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Perfluorocarbon emulsions radiosensitise brain tumors in carbogen breathing mice with orthotopic GL261 gliomas

BACKGROUND: Tumour hypoxia limits the effectiveness of radiation therapy. Delivering normobaric or hyperbaric oxygen therapy elevates pO(2) in both tumour and normal brain tissue. However, pO2 levels return to baseline within 15 minutes of stopping therapy. AIM: To investigate the effect of perfluor...

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Detalles Bibliográficos
Autores principales:	Feldman, Lisa A., Fabre, Marie-Sophie, Grasso, Carole, Reid, Dana, Broaddus, William C., Lanza, Gregory M., Spiess, Bruce D., Garbow, Joel R., McConnell, Melanie J., Herst, Patries M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584944/ https://www.ncbi.nlm.nih.gov/pubmed/28873460 http://dx.doi.org/10.1371/journal.pone.0184250

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