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HVAD Flow Waveform Morphologies: Theoretical Foundation and Implications for Clinical Practice

Continuous-flow ventricular assist device (cfVAD) performance and patient hemodynamic conditions are intimately interrelated and dynamic, changing frequently with alterations in physiologic conditions, particularly pre- and afterloading conditions. The Heartware cfVAD (HVAD) provides a unique featur...

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Detalles Bibliográficos
Autores principales: Rich, Jonathan D., Burkhoff, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585123/
https://www.ncbi.nlm.nih.gov/pubmed/28323662
http://dx.doi.org/10.1097/MAT.0000000000000557
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author Rich, Jonathan D.
Burkhoff, Daniel
author_facet Rich, Jonathan D.
Burkhoff, Daniel
author_sort Rich, Jonathan D.
collection PubMed
description Continuous-flow ventricular assist device (cfVAD) performance and patient hemodynamic conditions are intimately interrelated and dynamic, changing frequently with alterations in physiologic conditions, particularly pre- and afterloading conditions. The Heartware cfVAD (HVAD) provides a unique feature among currently approved VADs of providing an estimated instantaneous flow waveform, the characteristics of which can provide significant insights into patient and device properties. Despite being readily available, HVAD waveforms are poorly understood, underutilized, and insufficiently leveraged, even by clinicians who regularly manage HVAD patients. The purpose of this review is to provide the theoretical foundation for understanding the determinants of HVAD waveform characteristics and to provide practical examples illustrating how to interpret and integrate changes of HVAD waveforms into clinical practice. Heartware cfVAD waveforms should be considered a complimentary tool for the optimization of medical therapies and device speed in HVAD patients.
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spelling pubmed-55851232017-09-18 HVAD Flow Waveform Morphologies: Theoretical Foundation and Implications for Clinical Practice Rich, Jonathan D. Burkhoff, Daniel ASAIO J Review Article Continuous-flow ventricular assist device (cfVAD) performance and patient hemodynamic conditions are intimately interrelated and dynamic, changing frequently with alterations in physiologic conditions, particularly pre- and afterloading conditions. The Heartware cfVAD (HVAD) provides a unique feature among currently approved VADs of providing an estimated instantaneous flow waveform, the characteristics of which can provide significant insights into patient and device properties. Despite being readily available, HVAD waveforms are poorly understood, underutilized, and insufficiently leveraged, even by clinicians who regularly manage HVAD patients. The purpose of this review is to provide the theoretical foundation for understanding the determinants of HVAD waveform characteristics and to provide practical examples illustrating how to interpret and integrate changes of HVAD waveforms into clinical practice. Heartware cfVAD waveforms should be considered a complimentary tool for the optimization of medical therapies and device speed in HVAD patients. Lippincott Williams & Wilkins 2017-09 2017-08-31 /pmc/articles/PMC5585123/ /pubmed/28323662 http://dx.doi.org/10.1097/MAT.0000000000000557 Text en Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the ASAIO. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Review Article
Rich, Jonathan D.
Burkhoff, Daniel
HVAD Flow Waveform Morphologies: Theoretical Foundation and Implications for Clinical Practice
title HVAD Flow Waveform Morphologies: Theoretical Foundation and Implications for Clinical Practice
title_full HVAD Flow Waveform Morphologies: Theoretical Foundation and Implications for Clinical Practice
title_fullStr HVAD Flow Waveform Morphologies: Theoretical Foundation and Implications for Clinical Practice
title_full_unstemmed HVAD Flow Waveform Morphologies: Theoretical Foundation and Implications for Clinical Practice
title_short HVAD Flow Waveform Morphologies: Theoretical Foundation and Implications for Clinical Practice
title_sort hvad flow waveform morphologies: theoretical foundation and implications for clinical practice
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585123/
https://www.ncbi.nlm.nih.gov/pubmed/28323662
http://dx.doi.org/10.1097/MAT.0000000000000557
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