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VHH-Based Bispecific Antibodies Targeting Cytokine Production

Proinflammatory cytokines, such as TNF, IL-6, and IL-1, play pathogenic roles in multiple diseases and are attractive targets for biologic drugs. Because proinflammatory cytokines possess non-redundant protective and immunoregulatory functions, their systemic neutralization carries the potential for...

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Detalles Bibliográficos
Autores principales:	Nosenko, Maxim A., Atretkhany, Kamar-Sulu N., Mokhonov, Vladislav V., Efimov, Grigory A., Kruglov, Andrey A., Tillib, Sergei V., Drutskaya, Marina S., Nedospasov, Sergei A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585155/ https://www.ncbi.nlm.nih.gov/pubmed/28919896 http://dx.doi.org/10.3389/fimmu.2017.01073

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