A comprehensive characterization of the impact of mycophenolic acid on the metabolism of Jurkat T cells

Metabolic reprogramming is critical for T cell fate and polarization and is regulated by metabolic checkpoints, including Myc, HIF-1α, AMPK and mTORC1. Our objective was to determine the impact of mycophenolic acid (MPA) in comparison with rapamycin (Rapa), an inhibitor of mTORC1, on the metabolism...

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Detalles Bibliográficos
Autores principales: Fernández-Ramos, Ana A., Marchetti-Laurent, Catherine, Poindessous, Virginie, Antonio, Samantha, Petitgas, Céline, Ceballos-Picot, Irène, Laurent-Puig, Pierre, Bortoli, Sylvie, Loriot, Marie-Anne, Pallet, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585210/
https://www.ncbi.nlm.nih.gov/pubmed/28874730
http://dx.doi.org/10.1038/s41598-017-10338-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585210/
https://www.ncbi.nlm.nih.gov/pubmed/28874730
http://dx.doi.org/10.1038/s41598-017-10338-6

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