Cargando…

T-bet, but not Gata3, overexpression is detrimental in a neurotropic viral infection

Intracerebral Theiler’s murine encephalomyelitis virus (TMEV) infection in mice induces inflammatory demyelination in the central nervous system. Although C57BL/6 mice normally resistant to TMEV infection with viral clearance, we have previously demonstrated that RORγt-transgenic (tg) C57BL/6 mice,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sato, Fumitaka, Kawai, Eiichiro, Martinez, Nicholas E., Omura, Seiichi, Park, Ah-Mee, Takahashi, Satoru, Yoh, Keigyou, Tsunoda, Ikuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585213/ https://www.ncbi.nlm.nih.gov/pubmed/28874814 http://dx.doi.org/10.1038/s41598-017-10980-0

Ejemplares similares

Regulation of an Autoimmune Model for Multiple Sclerosis in Th2-Biased GATA3 Transgenic Mice
por: Fernando, Viromi, et al.
Publicado: (2014)

Th2-biased GATA-3 transgenic mice developed severe experimental peritoneal fibrosis compared with Th1-biased T-bet and Th17-biased RORγt transgenic mice
por: Yoh, Keigyou, et al.
Publicado: (2015)

Overexpression of GATA-3 in T Cells Accelerates Dextran Sulfate Sodium-Induced Colitis
por: Okamura, Midori, et al.
Publicado: (2014)

Bacterial and fungal isolation from face masks under the COVID-19 pandemic
por: Park, Ah-Mee, et al.
Publicado: (2022)

Adjuvant Injections Altered the Ileal and Fecal Microbiota Differently with Changes in Immunoglobulin Isotypes and Antimycobacterial Antibody Responses
por: Khadka, Sundar, et al.
Publicado: (2023)

Role of CD4(+) T Cells in the Pathophysiology of Multiple Sclerosis
por: Sato, Fumitaka, et al.
Publicado: (2016)

Galectin-3 as a Therapeutic Target for NSAID-Induced Intestinal Ulcers
por: Park, Ah-Mee, et al.
Publicado: (2020)

Beneficial and Detrimental Effects of Regulatory T Cells in Neurotropic Virus Infections
por: Ciurkiewicz, Malgorzata, et al.
Publicado: (2020)

Anti-Glycolipid Antibody Examination in Five EAE Models and Theiler’s Virus Model of Multiple Sclerosis: Detection of Anti-GM1, GM3, GM4, and Sulfatide Antibodies in Relapsing-Remitting EAE
por: Moriguchi, Kota, et al.
Publicado: (2023)

Curcumin β-D-Glucuronide Modulates an Autoimmune Model of Multiple Sclerosis with Altered Gut Microbiota in the Ileum and Feces
por: Khadka, Sundar, et al.
Publicado: (2021)

Corrigendum: Curcumin β-D-Glucuronide Modulates an Autoimmune Model of Multiple Sclerosis with Altered Gut Microbiota in the Ileum and Feces
por: Khadka, Sundar, et al.
Publicado: (2022)

Theiler's Virus-Mediated Immunopathology in the CNS and Heart: Roles of Organ-Specific Cytokine and Lymphatic Responses
por: Omura, Seiichi, et al.
Publicado: (2018)

Curdlan, a Microbial β-Glucan, Has Contrasting Effects on Autoimmune and Viral Models of Multiple Sclerosis
por: Sato, Fumitaka, et al.
Publicado: (2022)

Bioinformatics Analysis of Gut Microbiota and CNS Transcriptome in Virus-Induced Acute Myelitis and Chronic Inflammatory Demyelination; Potential Association of Distinct Bacteria With CNS IgA Upregulation
por: Omura, Seiichi, et al.
Publicado: (2020)

Bioinformatics Analyses Determined the Distinct CNS and Peripheral Surrogate Biomarker Candidates Between Two Mouse Models for Progressive Multiple Sclerosis
por: Omura, Seiichi, et al.
Publicado: (2019)

Overexpression of RORγt Enhances Pulmonary Inflammation after Infection with Mycobacterium Avium
por: Matsuyama, Masashi, et al.
Publicado: (2016)

“Microglial nodules” and “newly forming lesions” may be a Janus face of early MS lesions; implications from virus-induced demyelination, the Inside-Out model
por: Sato, Fumitaka, et al.
Publicado: (2015)

Gata3 is detrimental to regulatory T cell function in autoimmune diabetes
por: Kiaf, Badr, et al.
Publicado: (2023)

Involvement of RORγt-overexpressing T cells in the development of autoimmune arthritis in mice
por: Kondo, Yuya, et al.
Publicado: (2015)

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
por: Daussy, Cécile, et al.
Publicado: (2014)

Differentiation of IL-17-Producing Invariant Natural Killer T Cells Requires Expression of the Transcription Factor c-Maf
por: Yu, Jhang-Sian, et al.
Publicado: (2017)

Inflammation induces neuro-lymphatic protein expression in multiple sclerosis brain neurovasculature
por: Chaitanya, Ganta Vijay, et al.
Publicado: (2013)

Dynamic expression of T-bet and GATA3 by regulatory T cells maintains immune tolerance
por: Yu, Fang, et al.
Publicado: (2014)

GATA2 deficiency phenotype associated with tandem duplication of GATA2 and overexpression of GATA2-AS1
por: Singh, Preeti, et al.
Publicado: (2021)

Overexpression of T-bet, GATA-3 and TGF-ß Induces IFN-γ, IL-4/13A, and IL-17A Expression in Atlantic Salmon
por: Slettjord, Tiril H., et al.
Publicado: (2020)

Neurotropism of Salvarsan
Publicado: (1911)

Forensic luminol reaction for detecting fecal occult blood in experimental mice
por: Park, Ah-Mee, et al.
Publicado: (2018)

Helicobacter pylori infection in the stomach induces neuroinflammation: the potential roles of bacterial outer membrane vesicles in an animal model of Alzheimer’s disease
por: Park, Ah-Mee, et al.
Publicado: (2022)

The Diagnostic Value of Transcription Factors T-bet/GATA3 Ratio in Predicting Antibody-Mediated Rejection
por: Li, Xue, et al.
Publicado: (2013)

Lower expression of GATA3 and T-bet correlates with downregulated IL-10 in severe falciparum malaria
por: Mahanta, Anusree, et al.
Publicado: (2015)

Clinical significance of T-bet, GATA-3, and Bcl-6 transcription factor expression in bladder carcinoma
por: Bahria-Sediki, Islem Ben, et al.
Publicado: (2016)

Exploratory factor analysis determines latent factors in Guillain–Barré syndrome
por: Omura, Seiichi, et al.
Publicado: (2022)

Combined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells
por: Wiese, Maria, et al.
Publicado: (2020)

Neurotropic Coronavirus Infections
por: Perlman, Stanley, et al.
Publicado: (2016)

Neurotropic Astroviruses in Animals
por: Wildi, Nicole, et al.
Publicado: (2021)

Host and viral genetic factors which influence viral neurotropism
por: Tyler, Kenneth L.
Publicado: (1988)

Synaptic Plasticity and Neurological Disorders in Neurotropic Viral Infections
por: Atluri, Venkata Subba Rao, et al.
Publicado: (2015)

Differences in neurotropism and neurotoxicity among retrograde viral tracers
por: Sun, Leqiang, et al.
Publicado: (2019)

Astrocytes Are a Key Target for Neurotropic Viral Infection
por: Potokar, Maja, et al.
Publicado: (2023)

Expression of T-Bet, Eomesodermin, and GATA-3 Correlates With Distinct Phenotypes and Functional Properties in Porcine γδ T Cells
por: Rodríguez-Gómez, Irene M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_u3b4bp1i4bj1na9le7m4labgvr