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Antibody-dependent fragmentation is a newly identified mechanism of cell killing in vivo

The prevailing view is that therapeutic antibodies deplete cells through opsonization and subsequent phagocytosis, complement-dependent lysis or antibody-dependent cellular-cytotoxicity. We used high resolution in vivo imaging to identify a new antibody-dependent cell death pathway where Kupffer cel...

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Detalles Bibliográficos
Autores principales:	Liew, Pei Xiong, Kim, Jung Hwan, Lee, Woo-Yong, Kubes, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585239/ https://www.ncbi.nlm.nih.gov/pubmed/28874772 http://dx.doi.org/10.1038/s41598-017-10420-z

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