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The role of histone modification and a regulatory single-nucleotide polymorphism (rs2071166) in the Cx43 promoter in patients with TOF

Abnormal level of Cx43 expression could result in CHD. Epigenetic modification and disease-associated, non-coding SNPs might influence gene transcription and expression. Our study aimed to determine the role of histone modification and an rSNP (rs2071166) in the Cx43 promoter in patients with TOF. O...

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Detalles Bibliográficos
Autores principales: Gu, Ruoyi, Xu, Jun, Lin, Yixiang, Sheng, Wei, Ma, Duan, Ma, Xiaojing, Huang, Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585261/
https://www.ncbi.nlm.nih.gov/pubmed/28874875
http://dx.doi.org/10.1038/s41598-017-10756-6