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Altered cortico-striatal crosstalk underlies object recognition memory deficits in the sub-chronic phencyclidine model of schizophrenia

The neural mechanisms underlying cognitive deficits in schizophrenia are poorly understood. Sub-chronic treatment with the NMDA antagonist phencyclidine (PCP) produces cognitive abnormalities in rodents that reliably model aspects of the neurocognitive alterations observed in schizophrenia. Given th...

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Detalles Bibliográficos
Autores principales: Asif-Malik, Aman, Dautan, Daniel, Young, Andrew M. J., Gerdjikov, Todor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585296/
https://www.ncbi.nlm.nih.gov/pubmed/28293729
http://dx.doi.org/10.1007/s00429-017-1393-3