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Contribution of C1485T mutation in the HBx gene to human and murine hepatocarcinogenesis

Although Hepatitis B virus (HBV) X gene mutations are frequently detected in HBV-related human hepatocellular carcinoma (HCC) patients, causative HBx mutations in the development of HCC have not yet been determined. We herein identified C1485T and C1653T mutations in the HBx gene as independent risk...

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Detalles Bibliográficos
Autores principales: Hagiwara, Satoru, Nishida, Naoshi, Park, Ah-Mee, Komeda, Yoriaki, Sakurai, Toshiharu, Watanabe, Tomohiro, Kudo, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585302/
https://www.ncbi.nlm.nih.gov/pubmed/28874700
http://dx.doi.org/10.1038/s41598-017-10570-0