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Contribution of C1485T mutation in the HBx gene to human and murine hepatocarcinogenesis
Although Hepatitis B virus (HBV) X gene mutations are frequently detected in HBV-related human hepatocellular carcinoma (HCC) patients, causative HBx mutations in the development of HCC have not yet been determined. We herein identified C1485T and C1653T mutations in the HBx gene as independent risk...
Autores principales: | Hagiwara, Satoru, Nishida, Naoshi, Park, Ah-Mee, Komeda, Yoriaki, Sakurai, Toshiharu, Watanabe, Tomohiro, Kudo, Masatoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585302/ https://www.ncbi.nlm.nih.gov/pubmed/28874700 http://dx.doi.org/10.1038/s41598-017-10570-0 |
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