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Investigation of Mitochondrial Metabolic Response to Doxorubicin in Prostate Cancer Cells: An NADH, FAD and Tryptophan FLIM Assay

Prostate cancer (PCa) is one of the leading cancers in men in the USA. Lack of experimental tools that predict therapy response is one of the limitations of current therapeutic regimens. Mitochondrial dysfunctions including defective oxidative phosphorylation (OXPHOS) in cancer inhibit apoptosis by...

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Detalles Bibliográficos
Autores principales:	Alam, Shagufta Rehman, Wallrabe, Horst, Svindrych, Zdenek, Chaudhary, Ajay K., Christopher, Kathryn G., Chandra, Dhyan, Periasamy, Ammasi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585313/ https://www.ncbi.nlm.nih.gov/pubmed/28874842 http://dx.doi.org/10.1038/s41598-017-10856-3

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