Hyperactive TGF-β Signaling in Smooth Muscle Cells Exposed to HIV-protein(s) and Cocaine: Role in Pulmonary Vasculopathy

We earlier demonstrated synergistic increase in the proliferation of pulmonary smooth muscle cells on exposure to HIV-proteins and/or cocaine due to severe down-modulation of bone morphogenetic protein receptor (BMPR) axis: the anti-proliferative arm of TGF-β super family of receptors. Here, now we...

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Detalles Bibliográficos
Autores principales: Dalvi, Pranjali, Sharma, Himanshu, Konstantinova, Tomara, Sanderson, Miles, Brien-Ladner, Amy O’, Dhillon, Navneet K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585314/
https://www.ncbi.nlm.nih.gov/pubmed/28874783
http://dx.doi.org/10.1038/s41598-017-10438-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585314/
https://www.ncbi.nlm.nih.gov/pubmed/28874783
http://dx.doi.org/10.1038/s41598-017-10438-3

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