Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

Genomics-driven cancer therapeutics has gained prominence in personalized cancer treatment. However, its utility in indications lacking biomarker-driven treatment strategies remains limited. Here we present a “phenotype-driven precision-oncology” approach, based on the notion that biological respons...

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Detalles Bibliográficos
Autores principales: Chia, Shumei, Low, Joo-Leng, Zhang, Xiaoqian, Kwang, Xue-Lin, Chong, Fui-Teen, Sharma, Ankur, Bertrand, Denis, Toh, Shen Yon, Leong, Hui-Sun, Thangavelu, Matan T., Hwang, Jacqueline S. G., Lim, Kok-Hing, Skanthakumar, Thakshayeni, Tan, Hiang-Khoon, Su, Yan, Hui Choo, Siang, Hentze, Hannes, Tan, Iain B. H., Lezhava, Alexander, Tan, Patrick, Tan, Daniel S. W., Periyasamy, Giridharan, Koh, Judice L. Y., Gopalakrishna Iyer, N., DasGupta, Ramanuj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585361/
https://www.ncbi.nlm.nih.gov/pubmed/28874669
http://dx.doi.org/10.1038/s41467-017-00451-5

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