Cargando…

RETRACTED ARTICLE: Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer

Advanced prostate cancer (PCa) is a clinical challenge as no curative therapeutic is available. In this context, a better understanding of metastasis and resistance mechanisms in PCa is an important issue. As phosphatase and tensin homolog (PTEN) loss is the most common genetic lesion in such cancer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alioui, Anthony, Dufour, Julie, Leoni, Valerio, Loregger, Anke, Moeton, Martina, Iuliano, Luigi, Zerbinati, Chiara, Septier, Amandine, Val, Pierre, Fouache, Allan, Russo, Vincenzo, Volle, David H., Lobaccaro, Jean-Marc A., Zelcer, Noam, Baron, Silvère
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585406/ https://www.ncbi.nlm.nih.gov/pubmed/28874658 http://dx.doi.org/10.1038/s41467-017-00508-5

Ejemplares similares

Retraction Note: Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer
por: Alioui, Anthony, et al.
Publicado: (2018)

EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux
por: Nelson, Jessica Kristine, et al.
Publicado: (2017)

New Insights in Prostate Cancer Development and Tumor Therapy: Modulation of Nuclear Receptors and the Specific Role of Liver X Receptors
por: Bousset, Laura, et al.
Publicado: (2018)

Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene
por: Cook, Emma C. L., et al.
Publicado: (2017)

Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis
por: Loregger, Anke, et al.
Publicado: (2017)

Industrial Trans Fatty Acids Stimulate SREBP2‐Mediated Cholesterogenesis and Promote Non‐Alcoholic Fatty Liver Disease
por: Oteng, Antwi‐Boasiako, et al.
Publicado: (2019)

Lack of Liver X Receptors Leads to Cell Proliferation in a Model of Mouse Dorsal Prostate Epithelial Cell
por: Dufour, Julie, et al.
Publicado: (2013)

Liver X Receptors Protect from Development of Prostatic Intra-Epithelial Neoplasia in Mice
por: Pommier, Aurélien J. C., et al.
Publicado: (2013)

FBXW7 regulates endothelial barrier function by suppression of the cholesterol synthesis pathway and prenylation of RhoB
por: Pronk, Manon C. A., et al.
Publicado: (2019)

Drosophila Accessory Gland: A Complementary In Vivo Model to Bring New Insight to Prostate Cancer
por: Rambur, Amandine, et al.
Publicado: (2021)

LXRs, SHP, and FXR in Prostate Cancer: Enemies or Ménage à Quatre With AR?
por: Cariello, Marica, et al.
Publicado: (2018)

Liver X Receptors: A Possible Link between Lipid Disorders and Female Infertility
por: Dallel, Sarah, et al.
Publicado: (2018)

Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia
por: Bousset, Laura, et al.
Publicado: (2020)

Pharmacological Modulation of Steroid Activity in Hormone-Dependent Breast and Prostate Cancers: Effect of Some Plant Extract Derivatives
por: Bayala, Bagora, et al.
Publicado: (2020)

Sequential Ras/MAPK and PI3K/AKT/mTOR pathways recruitment drives basal extrusion in the prostate-like gland of Drosophila
por: Rambur, Amandine, et al.
Publicado: (2020)

Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans
por: Hendrix, Sebastian, et al.
Publicado: (2023)

The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate
por: Martinot, Emmanuelle, et al.
Publicado: (2017)

Chemical Composition of Essential Oil of Cymbopogon schoenanthus (L.) Spreng from Burkina Faso, and Effects against Prostate and Cervical Cancer Cell Lines
por: Bayala, Bagora, et al.
Publicado: (2023)

IL-27-Induced Type 1 Regulatory T-Cells Produce Oxysterols that Constrain IL-10 Production
por: Vigne, Solenne, et al.
Publicado: (2017)

Reduction in gut‐derived MUFAs via intestinal stearoyl‐CoA desaturase 1 deletion drives susceptibility to NAFLD and hepatocarcinoma
por: Ducheix, Simon, et al.
Publicado: (2022)

Epigenetic: a molecular link between testicular cancer and environmental exposures
por: Vega, Aurelie, et al.
Publicado: (2012)

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism
por: Loregger, Anke, et al.
Publicado: (2020)

Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice
por: van Loon, Nienke M., et al.
Publicado: (2018)

Bile acid-FXRα pathways regulate male sexual maturation in mice
por: Baptissart, Marine, et al.
Publicado: (2016)

Cholesterol: A Gatekeeper of Male Fertility?
por: Sèdes, Lauriane, et al.
Publicado: (2018)

Bile Acid Alters Male Mouse Fertility in Metabolic Syndrome Context
por: Vega, Aurélie, et al.
Publicado: (2015)

Cemented all-poly tibia in resource constrained country, affordable and cost-effective care. Is it applicable at this era? Review article
por: Kumar, Vickash, et al.
Publicado: (2019)

IDOL in metabolic, neurodegenerative and cardiovascular disease
por: van Loon, Nienke M., et al.
Publicado: (2018)

RETRACTED ARTICLE: Inhibited MicroRNA-301 Restrains Angiogenesis and Cell Growth in Esophageal Squamous Cell Carcinoma by Elevating PTEN
por: Wang, Bin, et al.
Publicado: (2021)

[Translated article] Significant Contribution of Spanish Dermatology Toward Understanding COVID-19: A Bibliometric Study of PubMed-Indexed Articles
por: Miñones-Ginarte, C., et al.
Publicado: (2022)

Proteolysis Targeting Chimeras (PROTACs): A Perspective on Integral Membrane Protein Degradation
por: Ruffilli, Camilla, et al.
Publicado: (2022)

Bile acid homeostasis controls CAR signaling pathways in mouse testis through FXRalpha
por: Martinot, Emmanuelle, et al.
Publicado: (2017)

Catalysis by the Tumor-Suppressor Enzymes PTEN and PTEN-L
por: Johnston, Sean B., et al.
Publicado: (2015)

Constrained by cadherins
por: Van Epps, Heather L.
Publicado: (2006)

Constraining Supersymmetry
por: Ellis, John R., et al.
Publicado: (2002)

The PTEN Conundrum: How to Target PTEN-Deficient Prostate Cancer
por: Turnham, Daniel J., et al.
Publicado: (2020)

The perfect PTEN – transcriptional regulation by PTEN dictates sarcoma identity
por: Langdon, Casey G., et al.
Publicado: (2021)

The effect of constraining eye-contact during dynamic emotional face perception—an fMRI study
por: Hadjikhani, Nouchine, et al.
Publicado: (2017)

PTEN Redundancy: Overexpressing lpten, a Homolog of Dictyostelium discoideum ptenA, the Ortholog of Human PTEN, Rescues All Behavioral Defects of the Mutant ptenA(−)
por: Lusche, Daniel F., et al.
Publicado: (2014)

Focusing of charged particles
por: Septier, Albert
Publicado: (1967)

Cannot write session to /tmp/vufind_sessions/sess_spads7kmdq8352nu5mhbdcf14c