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Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa

We report a 7-year-old girl with xeroderma pigmentosum (XP), who presented in our clinic with a large melanoma (35 × 50 × 20 mm, Breslow depth 18 mm) in the zygomatic-malar area. Palliative surgery was performed to maintain her residual vision and to reduce the pain caused by the compression of loca...

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Autores principales: Pillay, Kamlen, Adams, Saleigh, Vandermaesen, Laura, Hudson, Donald Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585435/
https://www.ncbi.nlm.nih.gov/pubmed/28894662
http://dx.doi.org/10.1097/GOX.0000000000001442
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author Pillay, Kamlen
Adams, Saleigh
Vandermaesen, Laura
Hudson, Donald Anthony
author_facet Pillay, Kamlen
Adams, Saleigh
Vandermaesen, Laura
Hudson, Donald Anthony
author_sort Pillay, Kamlen
collection PubMed
description We report a 7-year-old girl with xeroderma pigmentosum (XP), who presented in our clinic with a large melanoma (35 × 50 × 20 mm, Breslow depth 18 mm) in the zygomatic-malar area. Palliative surgery was performed to maintain her residual vision and to reduce the pain caused by the compression of local structures. Because of the limited access of autologous skin grafts in pediatric patients with XP who are severely affected, we opted to use an acellular dermal matrix. There was 100% graft uptake, and the pain due to compression by the tumor was alleviated. This case demonstrates that acellular dermal matrices can be safely and effectively used in oncological facial reconstruction, especially in patients with progressive conditions such as XP.
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spelling pubmed-55854352017-09-11 Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa Pillay, Kamlen Adams, Saleigh Vandermaesen, Laura Hudson, Donald Anthony Plast Reconstr Surg Glob Open Case Report We report a 7-year-old girl with xeroderma pigmentosum (XP), who presented in our clinic with a large melanoma (35 × 50 × 20 mm, Breslow depth 18 mm) in the zygomatic-malar area. Palliative surgery was performed to maintain her residual vision and to reduce the pain caused by the compression of local structures. Because of the limited access of autologous skin grafts in pediatric patients with XP who are severely affected, we opted to use an acellular dermal matrix. There was 100% graft uptake, and the pain due to compression by the tumor was alleviated. This case demonstrates that acellular dermal matrices can be safely and effectively used in oncological facial reconstruction, especially in patients with progressive conditions such as XP. Wolters Kluwer Health 2017-08-22 /pmc/articles/PMC5585435/ /pubmed/28894662 http://dx.doi.org/10.1097/GOX.0000000000001442 Text en Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Pillay, Kamlen
Adams, Saleigh
Vandermaesen, Laura
Hudson, Donald Anthony
Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_full Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_fullStr Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_full_unstemmed Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_short Acellular Dermal Matrix: Treating Periocular Melanoma in a Patient with Xeroderma Pigmentosa
title_sort acellular dermal matrix: treating periocular melanoma in a patient with xeroderma pigmentosa
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585435/
https://www.ncbi.nlm.nih.gov/pubmed/28894662
http://dx.doi.org/10.1097/GOX.0000000000001442
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