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Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial
BACKGROUND: Desflurane with a laryngeal mask airway may have advantages during ambulatory anesthesia. However, desflurane-induced airway irritability makes the use of desflurane challenging, especially in children. This study compared desflurane with sevoflurane maintenance anesthesia in terms of re...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585528/ https://www.ncbi.nlm.nih.gov/pubmed/28858134 http://dx.doi.org/10.1097/MD.0000000000007977 |
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author | Kim, Eun-Hee Song, In-Kyung Lee, Ji-Hyun Kim, Hee-Soo Kim, Hyun-Chang Yoon, Soo-Hyuk Jang, Young-Eun Kim, Jin-Tae |
author_facet | Kim, Eun-Hee Song, In-Kyung Lee, Ji-Hyun Kim, Hee-Soo Kim, Hyun-Chang Yoon, Soo-Hyuk Jang, Young-Eun Kim, Jin-Tae |
author_sort | Kim, Eun-Hee |
collection | PubMed |
description | BACKGROUND: Desflurane with a laryngeal mask airway may have advantages during ambulatory anesthesia. However, desflurane-induced airway irritability makes the use of desflurane challenging, especially in children. This study compared desflurane with sevoflurane maintenance anesthesia in terms of respiratory events and the emergence characteristics in children with a laryngeal mask airway. METHODS: This randomized controlled trial evaluated 200 children undergoing strabismus surgery allocated to desflurane or sevoflurane groups. After inducing anesthesia with sevoflurane and thiopental sodium 5 mg kg(−1), the anesthetic agent was changed to desflurane in the desflurane group, whereas sevoflurane was continued in the sevoflurane group. Respiratory events, emergence time, recovery time, and emergence agitation were compared between the groups. RESULTS: The overall respiratory events did not differ between the groups. However, the incidence of mild desaturation (90% ≤ SpO(2) < 97%) was significantly higher in the desflurane group (7%) than in the sevoflurane group (0%) (P = .007). Emergence was significantly faster in the desflurane group (6.6 ± 3.9 vs 8.0 ± 2.2 min, P = .003). The recovery time and emergence agitation in the postanesthesia care unit were comparable between groups. Laryngospasm developed in 5 children (1 in the sevoflurane group and 4 in the desflurane group, P = .365); of these, 4 patients were younger than 3 years. CONCLUSION: Desflurane maintenance anesthesia in children with a laryngeal mask airway shows a similar rate of overall respiratory events compared with sevoflurane anesthesia. However, anesthesiologists should be cautious of using desflurane in younger children concerning desaturation events during emergence. |
format | Online Article Text |
id | pubmed-5585528 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-55855282017-09-11 Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial Kim, Eun-Hee Song, In-Kyung Lee, Ji-Hyun Kim, Hee-Soo Kim, Hyun-Chang Yoon, Soo-Hyuk Jang, Young-Eun Kim, Jin-Tae Medicine (Baltimore) 3300 BACKGROUND: Desflurane with a laryngeal mask airway may have advantages during ambulatory anesthesia. However, desflurane-induced airway irritability makes the use of desflurane challenging, especially in children. This study compared desflurane with sevoflurane maintenance anesthesia in terms of respiratory events and the emergence characteristics in children with a laryngeal mask airway. METHODS: This randomized controlled trial evaluated 200 children undergoing strabismus surgery allocated to desflurane or sevoflurane groups. After inducing anesthesia with sevoflurane and thiopental sodium 5 mg kg(−1), the anesthetic agent was changed to desflurane in the desflurane group, whereas sevoflurane was continued in the sevoflurane group. Respiratory events, emergence time, recovery time, and emergence agitation were compared between the groups. RESULTS: The overall respiratory events did not differ between the groups. However, the incidence of mild desaturation (90% ≤ SpO(2) < 97%) was significantly higher in the desflurane group (7%) than in the sevoflurane group (0%) (P = .007). Emergence was significantly faster in the desflurane group (6.6 ± 3.9 vs 8.0 ± 2.2 min, P = .003). The recovery time and emergence agitation in the postanesthesia care unit were comparable between groups. Laryngospasm developed in 5 children (1 in the sevoflurane group and 4 in the desflurane group, P = .365); of these, 4 patients were younger than 3 years. CONCLUSION: Desflurane maintenance anesthesia in children with a laryngeal mask airway shows a similar rate of overall respiratory events compared with sevoflurane anesthesia. However, anesthesiologists should be cautious of using desflurane in younger children concerning desaturation events during emergence. Wolters Kluwer Health 2017-09-01 /pmc/articles/PMC5585528/ /pubmed/28858134 http://dx.doi.org/10.1097/MD.0000000000007977 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0 |
spellingShingle | 3300 Kim, Eun-Hee Song, In-Kyung Lee, Ji-Hyun Kim, Hee-Soo Kim, Hyun-Chang Yoon, Soo-Hyuk Jang, Young-Eun Kim, Jin-Tae Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial |
title | Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial |
title_full | Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial |
title_fullStr | Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial |
title_full_unstemmed | Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial |
title_short | Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial |
title_sort | desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: a randomized controlled trial |
topic | 3300 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585528/ https://www.ncbi.nlm.nih.gov/pubmed/28858134 http://dx.doi.org/10.1097/MD.0000000000007977 |
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