Cargando…

Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial

BACKGROUND: Desflurane with a laryngeal mask airway may have advantages during ambulatory anesthesia. However, desflurane-induced airway irritability makes the use of desflurane challenging, especially in children. This study compared desflurane with sevoflurane maintenance anesthesia in terms of re...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eun-Hee, Song, In-Kyung, Lee, Ji-Hyun, Kim, Hee-Soo, Kim, Hyun-Chang, Yoon, Soo-Hyuk, Jang, Young-Eun, Kim, Jin-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585528/
https://www.ncbi.nlm.nih.gov/pubmed/28858134
http://dx.doi.org/10.1097/MD.0000000000007977
_version_ 1783261646815232000
author Kim, Eun-Hee
Song, In-Kyung
Lee, Ji-Hyun
Kim, Hee-Soo
Kim, Hyun-Chang
Yoon, Soo-Hyuk
Jang, Young-Eun
Kim, Jin-Tae
author_facet Kim, Eun-Hee
Song, In-Kyung
Lee, Ji-Hyun
Kim, Hee-Soo
Kim, Hyun-Chang
Yoon, Soo-Hyuk
Jang, Young-Eun
Kim, Jin-Tae
author_sort Kim, Eun-Hee
collection PubMed
description BACKGROUND: Desflurane with a laryngeal mask airway may have advantages during ambulatory anesthesia. However, desflurane-induced airway irritability makes the use of desflurane challenging, especially in children. This study compared desflurane with sevoflurane maintenance anesthesia in terms of respiratory events and the emergence characteristics in children with a laryngeal mask airway. METHODS: This randomized controlled trial evaluated 200 children undergoing strabismus surgery allocated to desflurane or sevoflurane groups. After inducing anesthesia with sevoflurane and thiopental sodium 5 mg kg(−1), the anesthetic agent was changed to desflurane in the desflurane group, whereas sevoflurane was continued in the sevoflurane group. Respiratory events, emergence time, recovery time, and emergence agitation were compared between the groups. RESULTS: The overall respiratory events did not differ between the groups. However, the incidence of mild desaturation (90% ≤ SpO(2) < 97%) was significantly higher in the desflurane group (7%) than in the sevoflurane group (0%) (P = .007). Emergence was significantly faster in the desflurane group (6.6 ± 3.9 vs 8.0 ± 2.2 min, P = .003). The recovery time and emergence agitation in the postanesthesia care unit were comparable between groups. Laryngospasm developed in 5 children (1 in the sevoflurane group and 4 in the desflurane group, P = .365); of these, 4 patients were younger than 3 years. CONCLUSION: Desflurane maintenance anesthesia in children with a laryngeal mask airway shows a similar rate of overall respiratory events compared with sevoflurane anesthesia. However, anesthesiologists should be cautious of using desflurane in younger children concerning desaturation events during emergence.
format Online
Article
Text
id pubmed-5585528
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-55855282017-09-11 Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial Kim, Eun-Hee Song, In-Kyung Lee, Ji-Hyun Kim, Hee-Soo Kim, Hyun-Chang Yoon, Soo-Hyuk Jang, Young-Eun Kim, Jin-Tae Medicine (Baltimore) 3300 BACKGROUND: Desflurane with a laryngeal mask airway may have advantages during ambulatory anesthesia. However, desflurane-induced airway irritability makes the use of desflurane challenging, especially in children. This study compared desflurane with sevoflurane maintenance anesthesia in terms of respiratory events and the emergence characteristics in children with a laryngeal mask airway. METHODS: This randomized controlled trial evaluated 200 children undergoing strabismus surgery allocated to desflurane or sevoflurane groups. After inducing anesthesia with sevoflurane and thiopental sodium 5 mg kg(−1), the anesthetic agent was changed to desflurane in the desflurane group, whereas sevoflurane was continued in the sevoflurane group. Respiratory events, emergence time, recovery time, and emergence agitation were compared between the groups. RESULTS: The overall respiratory events did not differ between the groups. However, the incidence of mild desaturation (90% ≤ SpO(2) < 97%) was significantly higher in the desflurane group (7%) than in the sevoflurane group (0%) (P = .007). Emergence was significantly faster in the desflurane group (6.6 ± 3.9 vs 8.0 ± 2.2 min, P = .003). The recovery time and emergence agitation in the postanesthesia care unit were comparable between groups. Laryngospasm developed in 5 children (1 in the sevoflurane group and 4 in the desflurane group, P = .365); of these, 4 patients were younger than 3 years. CONCLUSION: Desflurane maintenance anesthesia in children with a laryngeal mask airway shows a similar rate of overall respiratory events compared with sevoflurane anesthesia. However, anesthesiologists should be cautious of using desflurane in younger children concerning desaturation events during emergence. Wolters Kluwer Health 2017-09-01 /pmc/articles/PMC5585528/ /pubmed/28858134 http://dx.doi.org/10.1097/MD.0000000000007977 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0
spellingShingle 3300
Kim, Eun-Hee
Song, In-Kyung
Lee, Ji-Hyun
Kim, Hee-Soo
Kim, Hyun-Chang
Yoon, Soo-Hyuk
Jang, Young-Eun
Kim, Jin-Tae
Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial
title Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial
title_full Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial
title_fullStr Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial
title_full_unstemmed Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial
title_short Desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: A randomized controlled trial
title_sort desflurane versus sevoflurane in pediatric anesthesia with a laryngeal mask airway: a randomized controlled trial
topic 3300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585528/
https://www.ncbi.nlm.nih.gov/pubmed/28858134
http://dx.doi.org/10.1097/MD.0000000000007977
work_keys_str_mv AT kimeunhee desfluraneversussevofluraneinpediatricanesthesiawithalaryngealmaskairwayarandomizedcontrolledtrial
AT songinkyung desfluraneversussevofluraneinpediatricanesthesiawithalaryngealmaskairwayarandomizedcontrolledtrial
AT leejihyun desfluraneversussevofluraneinpediatricanesthesiawithalaryngealmaskairwayarandomizedcontrolledtrial
AT kimheesoo desfluraneversussevofluraneinpediatricanesthesiawithalaryngealmaskairwayarandomizedcontrolledtrial
AT kimhyunchang desfluraneversussevofluraneinpediatricanesthesiawithalaryngealmaskairwayarandomizedcontrolledtrial
AT yoonsoohyuk desfluraneversussevofluraneinpediatricanesthesiawithalaryngealmaskairwayarandomizedcontrolledtrial
AT jangyoungeun desfluraneversussevofluraneinpediatricanesthesiawithalaryngealmaskairwayarandomizedcontrolledtrial
AT kimjintae desfluraneversussevofluraneinpediatricanesthesiawithalaryngealmaskairwayarandomizedcontrolledtrial