Low-Dose Ionizing Radiation Affects Mesenchymal Stem Cells via Extracellular Oxidized Cell-Free DNA: A Possible Mediator of Bystander Effect and Adaptive Response

We have hypothesized that the adaptive response to low doses of ionizing radiation (IR) is mediated by oxidized cell-free DNA (cfDNA) fragments. Here, we summarize our experimental evidence for this model. Studies involving measurements of ROS, expression of the NOX (superoxide radical production),...

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Detalles Bibliográficos
Autores principales: Sergeeva, V. A., Ershova, E. S., Veiko, N. N., Malinovskaya, E. M., Kalyanov, A. A., Kameneva, L. V., Stukalov, S. V., Dolgikh, O. A., Konkova, M. S., Ermakov, A. V., Veiko, V. P., Izhevskaya, V. L., Kutsev, S. I., Kostyuk, S. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585687/
https://www.ncbi.nlm.nih.gov/pubmed/28904740
http://dx.doi.org/10.1155/2017/9515809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585687/
https://www.ncbi.nlm.nih.gov/pubmed/28904740
http://dx.doi.org/10.1155/2017/9515809

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