Cordycepin induces apoptosis of human acute monocytic leukemia cells via downregulation of the ERK/Akt signaling pathway

The aim of the present study was to examine the apoptotic effect of cordycepin (COR) on human THP-1 acute monocytic leukemia cells. THP-1 cells were exposed to different concentrations of COR for 24, 48, 72 or 96 h. The cell viability and apoptotic rate were analyzed. The gene expression of Akt1, Ak...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Mo, Huimin, Gu, Jun, Chen, Kan, Han, Zhihua, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585717/
https://www.ncbi.nlm.nih.gov/pubmed/28912858
http://dx.doi.org/10.3892/etm.2017.4855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585717/
https://www.ncbi.nlm.nih.gov/pubmed/28912858
http://dx.doi.org/10.3892/etm.2017.4855

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