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A novel susceptibility locus in the IL12B region is associated with the pathophysiology of Takayasu arteritis through IL-12p40 and IL-12p70 production

BACKGROUND: A previous study revealed the association between susceptibility to Takayasu arteritis (TAK) and a single nucleotide polymorphism (SNP) rs6871626 located in IL12B, which encodes interleukin (IL)-12p40, a common component of IL-12p70 and IL-23. We investigated the expression of these cyto...

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Detalles Bibliográficos
Autores principales:	Nakajima, Toshiki, Yoshifuji, Hajime, Shimizu, Masakazu, Kitagori, Koji, Murakami, Kosaku, Nakashima, Ran, Imura, Yoshitaka, Tanaka, Masao, Ohmura, Koichiro, Matsuda, Fumihiko, Terao, Chikashi, Mimori, Tsuneyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585951/ https://www.ncbi.nlm.nih.gov/pubmed/28874185 http://dx.doi.org/10.1186/s13075-017-1408-8

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