Assessing the activity of nonsense-mediated mRNA decay in lung cancer

BACKGROUND: Inhibition of nonsense-mediated mRNA decay (NMD) in tumor cells can suppress tumor growth through expressing new antigens whose mRNAs otherwise are degraded by NMD. Thus NMD inhibition is a promising approach for developing cancer therapies. Apparently, the success of this approach relie...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Zhang, Peiwei, Zhu, Yufei, Kong, Xiangyin, Zhang, Zhenguo, Hu, Landian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586017/
https://www.ncbi.nlm.nih.gov/pubmed/28874147
http://dx.doi.org/10.1186/s12920-017-0292-z

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