Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration

Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) is associated with the accumulation of pathological neuronal and glial intracytoplasmic inclusions as well as accompanying neuron loss. We explored if cortical neurons detected by NeuN decreased with increasing TDP-43 inclusion path...

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Detalles Bibliográficos
Autores principales: Yousef, Ahmed, Robinson, John L., Irwin, David J., Byrne, Matthew D., Kwong, Linda K., Lee, Edward B., Xu, Yan, Xie, Sharon X., Rennert, Lior, Suh, EunRan, Van Deerlin, Vivianna M., Grossman, Murray, Lee, Virginia M.-Y., Trojanowski, John Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586052/
https://www.ncbi.nlm.nih.gov/pubmed/28877758
http://dx.doi.org/10.1186/s40478-017-0471-3

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