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Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013

BACKGROUND: Screening on multidrug-resistant tuberculosis (MDR-TB) has been limited to the serious TB subpopulations excluding the new TB patients. This study aimed to examine MDR-TB burden among the new TB patients. METHODS: We conducted a study in Zhejiang Province during 2009–2013 to screen for M...

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Autores principales: Peng, Ying, Chen, Song-Hua, Zhang, Le, Chen, Bin, Zhang, Ming-Wu, He, Tie-Niu, Wang, Fei, Chai, Cheng-Liang, Zhou, Lin, Zhang, Yu, Wang, Xiao-Meng, Jia, Zhongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586168/
https://www.ncbi.nlm.nih.gov/pubmed/28836544
http://dx.doi.org/10.4103/0366-6999.213413
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author Peng, Ying
Chen, Song-Hua
Zhang, Le
Chen, Bin
Zhang, Ming-Wu
He, Tie-Niu
Wang, Fei
Chai, Cheng-Liang
Zhou, Lin
Zhang, Yu
Wang, Xiao-Meng
Jia, Zhongwei
author_facet Peng, Ying
Chen, Song-Hua
Zhang, Le
Chen, Bin
Zhang, Ming-Wu
He, Tie-Niu
Wang, Fei
Chai, Cheng-Liang
Zhou, Lin
Zhang, Yu
Wang, Xiao-Meng
Jia, Zhongwei
author_sort Peng, Ying
collection PubMed
description BACKGROUND: Screening on multidrug-resistant tuberculosis (MDR-TB) has been limited to the serious TB subpopulations excluding the new TB patients. This study aimed to examine MDR-TB burden among the new TB patients. METHODS: We conducted a study in Zhejiang Province during 2009–2013 to screen for MDR-TB patients among the low MDR-TB risk patients and five subpopulations of high MDR-TB risk patients. The number, prevalence, and trend of MDR-TB were compared while the logistic regression model was used to examine risk factors related to MDR-TB. RESULTS: A total of 200 and 791 MDR-TB cases were, respectively, identified from the 9830 new TB cases and 2372 high-risk suspects who took MDR-TB screening from 2009 to 2013. The MDR-TB rates went down in both of the new TB patients and five MDR-TB high-risk groups over the study time, but the percentage of MDR-TB patients identified from the new TB patients in all diagnosed MDR-TB cases kept stable from 28.3% in 2011 to 27.0% in 2012 to 26.0% in 2013. CONCLUSIONS: The study indicated that MDR-TB burden among new TB patients was high, thus screening for MDR-TB among the new TB patients should be recommended in China as well as in the similar situation worldwide.
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spelling pubmed-55861682017-09-13 Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013 Peng, Ying Chen, Song-Hua Zhang, Le Chen, Bin Zhang, Ming-Wu He, Tie-Niu Wang, Fei Chai, Cheng-Liang Zhou, Lin Zhang, Yu Wang, Xiao-Meng Jia, Zhongwei Chin Med J (Engl) Original Article BACKGROUND: Screening on multidrug-resistant tuberculosis (MDR-TB) has been limited to the serious TB subpopulations excluding the new TB patients. This study aimed to examine MDR-TB burden among the new TB patients. METHODS: We conducted a study in Zhejiang Province during 2009–2013 to screen for MDR-TB patients among the low MDR-TB risk patients and five subpopulations of high MDR-TB risk patients. The number, prevalence, and trend of MDR-TB were compared while the logistic regression model was used to examine risk factors related to MDR-TB. RESULTS: A total of 200 and 791 MDR-TB cases were, respectively, identified from the 9830 new TB cases and 2372 high-risk suspects who took MDR-TB screening from 2009 to 2013. The MDR-TB rates went down in both of the new TB patients and five MDR-TB high-risk groups over the study time, but the percentage of MDR-TB patients identified from the new TB patients in all diagnosed MDR-TB cases kept stable from 28.3% in 2011 to 27.0% in 2012 to 26.0% in 2013. CONCLUSIONS: The study indicated that MDR-TB burden among new TB patients was high, thus screening for MDR-TB among the new TB patients should be recommended in China as well as in the similar situation worldwide. Medknow Publications & Media Pvt Ltd 2017-09-05 /pmc/articles/PMC5586168/ /pubmed/28836544 http://dx.doi.org/10.4103/0366-6999.213413 Text en Copyright: © 2017 Chinese Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Peng, Ying
Chen, Song-Hua
Zhang, Le
Chen, Bin
Zhang, Ming-Wu
He, Tie-Niu
Wang, Fei
Chai, Cheng-Liang
Zhou, Lin
Zhang, Yu
Wang, Xiao-Meng
Jia, Zhongwei
Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013
title Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013
title_full Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013
title_fullStr Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013
title_full_unstemmed Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013
title_short Multidrug-resistant Tuberculosis Burden among the New Tuberculosis Patients in Zhejiang Province: An Observational Study, 2009–2013
title_sort multidrug-resistant tuberculosis burden among the new tuberculosis patients in zhejiang province: an observational study, 2009–2013
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586168/
https://www.ncbi.nlm.nih.gov/pubmed/28836544
http://dx.doi.org/10.4103/0366-6999.213413
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