A Soluble Fluorescent Binding Assay Reveals PIP(2) Antagonism of TREK-1 Channels

Lipid regulation of ion channels by low-abundance signaling lipids phosphatidylinositol 4,5-bisphosphate (PIP(2)) and phosphatidic acid (PA) has emerged as a central cellular mechanism for controlling ion channels and the excitability of nerves. A lack of robust assays suitable for facile detection...

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Detalles Bibliográficos
Autores principales: Cabanos, Cerrone, Wang, Miao, Han, Xianlin, Hansen, Scott B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586213/
https://www.ncbi.nlm.nih.gov/pubmed/28793254
http://dx.doi.org/10.1016/j.celrep.2017.07.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586213/
https://www.ncbi.nlm.nih.gov/pubmed/28793254
http://dx.doi.org/10.1016/j.celrep.2017.07.034

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