PP2A-B′ holoenzyme substrate recognition, regulation and role in cytokinesis

Protein phosphatase 2A (PP2A) is a major Ser/Thr phosphatase; it forms diverse heterotrimeric holoenzymes that counteract kinase actions. Using a peptidome that tiles the disordered regions of the human proteome, we identified proteins containing [LMFI]xx[ILV]xEx motifs that serve as interaction sit...

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Detalles Bibliográficos
Autores principales: Wu, Cheng-Guo, Chen, Hui, Guo, Feng, Yadav, Vikash K, Mcilwain, Sean J, Rowse, Michael, Choudhary, Alka, Lin, Ziqing, Li, Yitong, Gu, Tingjia, Zheng, Aiping, Xu, Qingge, Lee, Woojong, Resch, Eduard, Johnson, Benjamin, Day, Jenny, Ge, Ying, Ong, Irene M, Burkard, Mark E, Ivarsson, Ylva, Xing, Yongna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586252/
https://www.ncbi.nlm.nih.gov/pubmed/28884018
http://dx.doi.org/10.1038/celldisc.2017.27

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