Cargando…

Implications of American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Guidelines on Statin Underutilization for Prevention of Cardiovascular Disease in Diabetes Mellitus Among Several US Networks of Community Health Centers

BACKGROUND: Little is known about statin underutilization among diabetes mellitus patients cared for in community health centers, which tend to serve socioeconomically disadvantaged populations. Implications of the American College of Cardiology/American Heart Association (ACC/AHA) guidelines on pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Akhabue, Ehimare, Rittner, Sarah S., Carroll, Joseph E., Crawford, Phillip M., Dant, Lydia, Laws, Reesa, Leo, Michael C., Puro, Jon, Persell, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586289/
https://www.ncbi.nlm.nih.gov/pubmed/28673901
http://dx.doi.org/10.1161/JAHA.117.005627
_version_ 1783261787428225024
author Akhabue, Ehimare
Rittner, Sarah S.
Carroll, Joseph E.
Crawford, Phillip M.
Dant, Lydia
Laws, Reesa
Leo, Michael C.
Puro, Jon
Persell, Stephen D.
author_facet Akhabue, Ehimare
Rittner, Sarah S.
Carroll, Joseph E.
Crawford, Phillip M.
Dant, Lydia
Laws, Reesa
Leo, Michael C.
Puro, Jon
Persell, Stephen D.
author_sort Akhabue, Ehimare
collection PubMed
description BACKGROUND: Little is known about statin underutilization among diabetes mellitus patients cared for in community health centers, which tend to serve socioeconomically disadvantaged populations. Implications of the American College of Cardiology/American Heart Association (ACC/AHA) guidelines on preexisting gaps in statin treatment in this population are unclear. METHODS AND RESULTS: We included 32 440 adults (45% male, 63% nonwhite, 29% uninsured/Medicaid) aged 40 to 75 years with diabetes mellitus who received care within 16 community health center groups in 11 states in the Community Health Applied Research Network during 2013. Statin prescribing was analyzed as a function of concordance with the National Cholesterol Education Program Adult Treatment Panel 2001 and ACC/AHA 2013 guidelines. More patients’ treatments were concordant with the ACC/AHA (52.8%) versus the National Cholesterol Education Program Adult Treatment Panel (36.2%) guideline. Female sex was associated with lower concordance for both (odds ratio [OR] 0.90, CI 0.85‐0.94; and OR 0.84, CI 0.80‐0.88, respectively). Being insured, an Asian/Pacific Islander, or primarily Spanish speaking were associated with greater concordance for both guidelines: 35.5% (11 526/32 440) were concordant with neither guideline, the majority (79.7%) having no statin prescribed; 28.2% (9168/32 440) were concordant with ACC/AHA but not the National Cholesterol Education Program Adult Treatment Panel. 8.7% of these patients had a low‐density lipoprotein cholesterol >160 mg/dL despite having a moderate‐ or high‐intensity statin prescribed. And 11.6% (3772/32 440) were concordant with the National Cholesterol Education Program Adult Treatment Panel but not with ACC/AHA. Most of these patients had a low‐density lipoprotein cholesterol between 70 and 99 mg/dL with no or a low‐intensity statin prescribed. CONCLUSIONS: Opportunities exist to improve cholesterol management in diabetes mellitus patients in community health centers. Addressing care gaps could improve cardiovascular disease prevention in this high‐risk population.
format Online
Article
Text
id pubmed-5586289
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-55862892017-09-11 Implications of American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Guidelines on Statin Underutilization for Prevention of Cardiovascular Disease in Diabetes Mellitus Among Several US Networks of Community Health Centers Akhabue, Ehimare Rittner, Sarah S. Carroll, Joseph E. Crawford, Phillip M. Dant, Lydia Laws, Reesa Leo, Michael C. Puro, Jon Persell, Stephen D. J Am Heart Assoc Original Research BACKGROUND: Little is known about statin underutilization among diabetes mellitus patients cared for in community health centers, which tend to serve socioeconomically disadvantaged populations. Implications of the American College of Cardiology/American Heart Association (ACC/AHA) guidelines on preexisting gaps in statin treatment in this population are unclear. METHODS AND RESULTS: We included 32 440 adults (45% male, 63% nonwhite, 29% uninsured/Medicaid) aged 40 to 75 years with diabetes mellitus who received care within 16 community health center groups in 11 states in the Community Health Applied Research Network during 2013. Statin prescribing was analyzed as a function of concordance with the National Cholesterol Education Program Adult Treatment Panel 2001 and ACC/AHA 2013 guidelines. More patients’ treatments were concordant with the ACC/AHA (52.8%) versus the National Cholesterol Education Program Adult Treatment Panel (36.2%) guideline. Female sex was associated with lower concordance for both (odds ratio [OR] 0.90, CI 0.85‐0.94; and OR 0.84, CI 0.80‐0.88, respectively). Being insured, an Asian/Pacific Islander, or primarily Spanish speaking were associated with greater concordance for both guidelines: 35.5% (11 526/32 440) were concordant with neither guideline, the majority (79.7%) having no statin prescribed; 28.2% (9168/32 440) were concordant with ACC/AHA but not the National Cholesterol Education Program Adult Treatment Panel. 8.7% of these patients had a low‐density lipoprotein cholesterol >160 mg/dL despite having a moderate‐ or high‐intensity statin prescribed. And 11.6% (3772/32 440) were concordant with the National Cholesterol Education Program Adult Treatment Panel but not with ACC/AHA. Most of these patients had a low‐density lipoprotein cholesterol between 70 and 99 mg/dL with no or a low‐intensity statin prescribed. CONCLUSIONS: Opportunities exist to improve cholesterol management in diabetes mellitus patients in community health centers. Addressing care gaps could improve cardiovascular disease prevention in this high‐risk population. John Wiley and Sons Inc. 2017-07-03 /pmc/articles/PMC5586289/ /pubmed/28673901 http://dx.doi.org/10.1161/JAHA.117.005627 Text en © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
Akhabue, Ehimare
Rittner, Sarah S.
Carroll, Joseph E.
Crawford, Phillip M.
Dant, Lydia
Laws, Reesa
Leo, Michael C.
Puro, Jon
Persell, Stephen D.
Implications of American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Guidelines on Statin Underutilization for Prevention of Cardiovascular Disease in Diabetes Mellitus Among Several US Networks of Community Health Centers
title Implications of American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Guidelines on Statin Underutilization for Prevention of Cardiovascular Disease in Diabetes Mellitus Among Several US Networks of Community Health Centers
title_full Implications of American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Guidelines on Statin Underutilization for Prevention of Cardiovascular Disease in Diabetes Mellitus Among Several US Networks of Community Health Centers
title_fullStr Implications of American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Guidelines on Statin Underutilization for Prevention of Cardiovascular Disease in Diabetes Mellitus Among Several US Networks of Community Health Centers
title_full_unstemmed Implications of American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Guidelines on Statin Underutilization for Prevention of Cardiovascular Disease in Diabetes Mellitus Among Several US Networks of Community Health Centers
title_short Implications of American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Guidelines on Statin Underutilization for Prevention of Cardiovascular Disease in Diabetes Mellitus Among Several US Networks of Community Health Centers
title_sort implications of american college of cardiology/american heart association (acc/aha) cholesterol guidelines on statin underutilization for prevention of cardiovascular disease in diabetes mellitus among several us networks of community health centers
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586289/
https://www.ncbi.nlm.nih.gov/pubmed/28673901
http://dx.doi.org/10.1161/JAHA.117.005627
work_keys_str_mv AT akhabueehimare implicationsofamericancollegeofcardiologyamericanheartassociationaccahacholesterolguidelinesonstatinunderutilizationforpreventionofcardiovasculardiseaseindiabetesmellitusamongseveralusnetworksofcommunityhealthcenters
AT rittnersarahs implicationsofamericancollegeofcardiologyamericanheartassociationaccahacholesterolguidelinesonstatinunderutilizationforpreventionofcardiovasculardiseaseindiabetesmellitusamongseveralusnetworksofcommunityhealthcenters
AT carrolljosephe implicationsofamericancollegeofcardiologyamericanheartassociationaccahacholesterolguidelinesonstatinunderutilizationforpreventionofcardiovasculardiseaseindiabetesmellitusamongseveralusnetworksofcommunityhealthcenters
AT crawfordphillipm implicationsofamericancollegeofcardiologyamericanheartassociationaccahacholesterolguidelinesonstatinunderutilizationforpreventionofcardiovasculardiseaseindiabetesmellitusamongseveralusnetworksofcommunityhealthcenters
AT dantlydia implicationsofamericancollegeofcardiologyamericanheartassociationaccahacholesterolguidelinesonstatinunderutilizationforpreventionofcardiovasculardiseaseindiabetesmellitusamongseveralusnetworksofcommunityhealthcenters
AT lawsreesa implicationsofamericancollegeofcardiologyamericanheartassociationaccahacholesterolguidelinesonstatinunderutilizationforpreventionofcardiovasculardiseaseindiabetesmellitusamongseveralusnetworksofcommunityhealthcenters
AT leomichaelc implicationsofamericancollegeofcardiologyamericanheartassociationaccahacholesterolguidelinesonstatinunderutilizationforpreventionofcardiovasculardiseaseindiabetesmellitusamongseveralusnetworksofcommunityhealthcenters
AT purojon implicationsofamericancollegeofcardiologyamericanheartassociationaccahacholesterolguidelinesonstatinunderutilizationforpreventionofcardiovasculardiseaseindiabetesmellitusamongseveralusnetworksofcommunityhealthcenters
AT persellstephend implicationsofamericancollegeofcardiologyamericanheartassociationaccahacholesterolguidelinesonstatinunderutilizationforpreventionofcardiovasculardiseaseindiabetesmellitusamongseveralusnetworksofcommunityhealthcenters