Cargando…

Platelet‐Derived Factor V Is a Critical Mediator of Arterial Thrombosis

BACKGROUND: Coagulation factor V (FV) plays a key role in hemostasis, is present in plasma and platelets, and has both pro‐ and anticoagulant properties; however, the contribution of platelet‐derived FV to arterial thrombosis remains undetermined. METHODS AND RESULTS: Using transgenic mice with vari...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Meiping, Li, Rong, Chen, Ni, Pang, Ningbo, Li, Yongjie, Deng, Xin, Wang, Liqun, Luo, Mao, Liu, Yan, Hao, Haiyan, Liu, Yong, Sun, Hongmin, Wu, Jianbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586322/ https://www.ncbi.nlm.nih.gov/pubmed/28673898 http://dx.doi.org/10.1161/JAHA.117.006345

Ejemplares similares

Polydatin Prevents Methylglyoxal-Induced Apoptosis through Reducing Oxidative Stress and Improving Mitochondrial Function in Human Umbilical Vein Endothelial Cells
por: Pang, Ningbo, et al.
Publicado: (2017)

Angiopoietin-2 impairs collateral artery growth associated with the suppression of the infiltration of macrophages in mouse hindlimb ischaemia
por: Tan, Xiaoyong, et al.
Publicado: (2016)

Platelet-Derived Factor V Is an Important Determinant of the Metastatic Potential of Circulating Tumor Cells
por: Deng, Xin, et al.
Publicado: (2020)

Hyperglycaemia-induced reciprocal changes in miR-30c and PAI-1 expression in platelets
por: Luo, Mao, et al.
Publicado: (2016)

MiRNA-21 mediates the antiangiogenic activity of metformin through targeting PTEN and SMAD7 expression and PI3K/AKT pathway
por: Luo, Mao, et al.
Publicado: (2017)

Bevacizumab promotes venous thromboembolism through the induction of PAI-1 in a mouse xenograft model of human lung carcinoma
por: Chen, Ni, et al.
Publicado: (2015)

Linagliptin Regulates the Mitochondrial Respiratory Reserve to Alter Platelet Activation and Arterial Thrombosis
por: Li, Yi, et al.
Publicado: (2020)

Transplantation of Normal Adipose Tissue Improves Blood Flow and Reduces Inflammation in High Fat Fed Mice With Hindlimb Ischemia
por: Chen, Liyuan, et al.
Publicado: (2018)

Corrigendum: Transplantation of Normal Adipose Tissue Improves Blood Flow and Reduces Inflammation in High Fat Fed Mice With Hindlimb Ischemia
por: Chen, Liyuan, et al.
Publicado: (2018)

Presence of intratumoral platelets is associated with tumor vessel structure and metastasis
por: Li, Rong, et al.
Publicado: (2014)

Glycation of fibronectin inhibits VEGF‐induced angiogenesis by uncoupling VEGF receptor‐2‐c‐Src crosstalk
por: Chen, Tangting, et al.
Publicado: (2020)

MG53 inhibits angiogenesis through regulating focal adhesion kinase signalling
por: Dong, Jinling, et al.
Publicado: (2021)

Glycation of Tie-2 Inhibits Angiopoietin-1 Signaling Activation and Angiopoietin-1-Induced Angiogenesis
por: Zhou, Haiyan, et al.
Publicado: (2022)

Vitronectin Increases Vascular Permeability by Promoting VE-Cadherin Internalization at Cell Junctions
por: Li, Rong, et al.
Publicado: (2012)

Beyond Thrombosis: The Versatile Platelet in Critical Illness
por: Katz, Jason N., et al.
Publicado: (2011)

Rapamycin promoted thrombosis and platelet adhesion to endothelial cells by inducing membrane remodeling
por: Jiang, Ping, et al.
Publicado: (2014)

Platelet phosphatidylserine is the critical mediator of thrombosis in heparin-induced thrombocytopenia
por: Zlamal, Jan, et al.
Publicado: (2023)

Critical role of peroxisome proliferator-activated receptor a in promoting platelet hyperreactivity and thrombosis under hyperlipidemia
por: Li, Li, et al.
Publicado: (2021)

Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation
por: Pircher, Joachim, et al.
Publicado: (2018)

Novel Therapeutic Agent against Platelet Activation In Vitro and Arterial Thrombosis In Vivo by Morin Hydrate
por: Hsia, Chih-Wei, et al.
Publicado: (2018)

Antagonizing αvβ3 Integrin Improves Ischemia-Mediated Vascular Normalization and Blood Perfusion by Altering Macrophages
por: Li, Yongjie, et al.
Publicado: (2021)

Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo
por: Momi, Stefania, et al.
Publicado: (2009)

Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapies
por: Xu, Xiaohong Ruby, et al.
Publicado: (2016)

NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis
por: Qiao, Jianlin, et al.
Publicado: (2018)

Regulation of Human Platelet Activation and Prevention of Arterial Thrombosis in Mice by Auraptene through Inhibition of NF-κB Pathway
por: Hsia, Chih-Wei, et al.
Publicado: (2020)

Point-of-care platelet function tests: relevance to arterial thrombosis and opportunities for improvement
por: Gorog, Diana A., et al.
Publicado: (2020)

Cancer and Thrombosis: The Platelet Perspective
por: Meikle, Claire K. S., et al.
Publicado: (2017)

Platelet Aggregation Tests and Thrombosis
por: O'Brien, J. R.
Publicado: (1969)

Platelets as Mediators of Neuroinflammation and Thrombosis
por: Rawish, Elias, et al.
Publicado: (2020)

Platelet–Neutrophil Crosstalk in Thrombosis
por: Mereweather, Laura J., et al.
Publicado: (2023)

TRAF3 negatively regulates platelet activation and thrombosis
por: Zhang, Rui, et al.
Publicado: (2017)

Naringenin Inhibits Platelet Activation and Arterial Thrombosis Through Inhibition of Phosphoinositide 3-Kinase and Cyclic Nucleotide Signaling
por: Huang, Manting, et al.
Publicado: (2021)

Prevention of platelet aggregation and arterial thrombosis using a modified Shenzhu Guanxin Formula
por: Huang, Manting, et al.
Publicado: (2020)

Structure of shear-induced platelet aggregated clot formed in an in vitro arterial thrombosis model
por: Kim, Dongjune A., et al.
Publicado: (2022)

Occlusive thrombosis in arteries
por: Kim, Dongjune, et al.
Publicado: (2019)

Effect of Antrodia camphorata on Inflammatory Arterial Thrombosis-Mediated Platelet Activation: The Pivotal Role of Protein Kinase C
por: Lu, Wan-Jung, et al.
Publicado: (2014)

In situ transplantation of adipose-derived stem cells via photoactivation improves glucose metabolism in obese mice
por: Zhu, Luochen, et al.
Publicado: (2021)

The Role of Platelet-Derived Extracellular Vesicles in Immune-Mediated Thrombosis
por: Eustes, Alicia S., et al.
Publicado: (2022)

Platelets in the NETworks interweaving inflammation and thrombosis
por: Wienkamp, Ann-Katrin, et al.
Publicado: (2022)

Effects of Danshensu on Platelet Aggregation and Thrombosis: In Vivo Arteriovenous Shunt and Venous Thrombosis Models in Rats
por: Yu, Chen, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_h0226cb06br80abs8qd4amlp9u