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Contrasting Determinants of Mutation Rates in Germline and Soma
Recent studies of somatic and germline mutations have led to the identification of a number of factors that influence point mutation rates, including CpG methylation, expression levels, replication timing, and GC content. Intriguingly, some of the effects appear to differ between soma and germline:...
Autores principales: | Chen, Chen, Qi, Hongjian, Shen, Yufeng, Pickrell, Joseph, Przeworski, Molly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586376/ https://www.ncbi.nlm.nih.gov/pubmed/28733365 http://dx.doi.org/10.1534/genetics.117.1114 |
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