Fever and Psychosis as an Early Presentation of Brucella-Associated Meningoencephalitis: A Case Report

OBJECTIVE: To describe a case with Brucella-associated meningoencephalitis. In addition, we report drug-induced hepatotoxicity due to acyclovir. CLINICAL PRESENTATION AND INTERVENTION: A young woman was admitted with fever and psychosis and neuroimaging findings indicative of meningoencephalitis. Se...

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Autores principales: Montazeri, Mahnaz, Sadeghi, Kourosh, Khalili, Hosein, Davoudi, Setareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586770/
https://www.ncbi.nlm.nih.gov/pubmed/23295541
http://dx.doi.org/10.1159/000345640
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author Montazeri, Mahnaz
Sadeghi, Kourosh
Khalili, Hosein
Davoudi, Setareh
author_facet Montazeri, Mahnaz
Sadeghi, Kourosh
Khalili, Hosein
Davoudi, Setareh
author_sort Montazeri, Mahnaz
collection PubMed
description OBJECTIVE: To describe a case with Brucella-associated meningoencephalitis. In addition, we report drug-induced hepatotoxicity due to acyclovir. CLINICAL PRESENTATION AND INTERVENTION: A young woman was admitted with fever and psychosis and neuroimaging findings indicative of meningoencephalitis. Serology was positive for Brucella. She was treated with doxycycline, rifampin, and trimethoprim-sulfamethoxazole. CONCLUSION: This case reminds physicians in endemic regions to consider neurobrucellosis as a differential diagnosis in patients with any unexplained neurologic symptoms or atypical psychosis. Early diagnosis and treatment of neurobrucellosis will be helpful in decreasing the sequelae of this complication.
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spelling pubmed-55867702017-11-01 Fever and Psychosis as an Early Presentation of Brucella-Associated Meningoencephalitis: A Case Report Montazeri, Mahnaz Sadeghi, Kourosh Khalili, Hosein Davoudi, Setareh Med Princ Pract Case Report OBJECTIVE: To describe a case with Brucella-associated meningoencephalitis. In addition, we report drug-induced hepatotoxicity due to acyclovir. CLINICAL PRESENTATION AND INTERVENTION: A young woman was admitted with fever and psychosis and neuroimaging findings indicative of meningoencephalitis. Serology was positive for Brucella. She was treated with doxycycline, rifampin, and trimethoprim-sulfamethoxazole. CONCLUSION: This case reminds physicians in endemic regions to consider neurobrucellosis as a differential diagnosis in patients with any unexplained neurologic symptoms or atypical psychosis. Early diagnosis and treatment of neurobrucellosis will be helpful in decreasing the sequelae of this complication. S. Karger AG 2013-09 2013-01-05 /pmc/articles/PMC5586770/ /pubmed/23295541 http://dx.doi.org/10.1159/000345640 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
spellingShingle Case Report
Montazeri, Mahnaz
Sadeghi, Kourosh
Khalili, Hosein
Davoudi, Setareh
Fever and Psychosis as an Early Presentation of Brucella-Associated Meningoencephalitis: A Case Report
title Fever and Psychosis as an Early Presentation of Brucella-Associated Meningoencephalitis: A Case Report
title_full Fever and Psychosis as an Early Presentation of Brucella-Associated Meningoencephalitis: A Case Report
title_fullStr Fever and Psychosis as an Early Presentation of Brucella-Associated Meningoencephalitis: A Case Report
title_full_unstemmed Fever and Psychosis as an Early Presentation of Brucella-Associated Meningoencephalitis: A Case Report
title_short Fever and Psychosis as an Early Presentation of Brucella-Associated Meningoencephalitis: A Case Report
title_sort fever and psychosis as an early presentation of brucella-associated meningoencephalitis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586770/
https://www.ncbi.nlm.nih.gov/pubmed/23295541
http://dx.doi.org/10.1159/000345640
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