Cargando…

Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study

OBJECTIVE: To determine the relationship between rosacea, chronic rhinosinusitis (CRS), and the clinical presentation of rosacea. SUBJECTS AND METHOD: Twenty-eight female Saudi patients diagnosed with rosacea at the Dermatology Clinic, King Khalid University Hospital, King Saud University, Riyadh, S...

Descripción completa

Detalles Bibliográficos
Autor principal: Al-Balbeesi, Amal O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586923/
https://www.ncbi.nlm.nih.gov/pubmed/25060422
http://dx.doi.org/10.1159/000364905
_version_ 1783261906943868928
author Al-Balbeesi, Amal O.
author_facet Al-Balbeesi, Amal O.
author_sort Al-Balbeesi, Amal O.
collection PubMed
description OBJECTIVE: To determine the relationship between rosacea, chronic rhinosinusitis (CRS), and the clinical presentation of rosacea. SUBJECTS AND METHOD: Twenty-eight female Saudi patients diagnosed with rosacea at the Dermatology Clinic, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia, between September 2011 and September 2012 and 20 age- and sex-matched control patients were included in the study. Paranasal sinus X-rays and assessments of the serum concentration of IgE (ImmunoCAP test; Phadia Laboratory Systems) were performed in both groups. RESULT: The rosacea patients had significantly more radiological evidence of CRS than the patients without rosacea [19 (67.9%) vs. 4 (20%), p = 0.003]. The median IgE concentration was similar in both groups (225.4 vs. 223.1 kU/l). Nine rosacea patients (32.1%) without radiological evidence of CRS did not have a significantly different median concentration of IgE compared with those who had radiological evidence of CRS (190.5 vs. 111.5 kU/l, p = 0.859). Erythematotelangiectatic severity was significantly associated with CRS (p = 0.038). Serum IgE did not correlate with the severity of the facial condition. CONCLUSION: Patients with rosacea and CRS manifested severe erythematotelangiectatic rosacea. There was enough evidence to suggest an association between rosacea and CRS. Clinical and radiological assessments of the paranasal sinuses are recommended.
format Online
Article
Text
id pubmed-5586923
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher S. Karger AG
record_format MEDLINE/PubMed
spelling pubmed-55869232017-11-01 Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study Al-Balbeesi, Amal O. Med Princ Pract Original Paper OBJECTIVE: To determine the relationship between rosacea, chronic rhinosinusitis (CRS), and the clinical presentation of rosacea. SUBJECTS AND METHOD: Twenty-eight female Saudi patients diagnosed with rosacea at the Dermatology Clinic, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia, between September 2011 and September 2012 and 20 age- and sex-matched control patients were included in the study. Paranasal sinus X-rays and assessments of the serum concentration of IgE (ImmunoCAP test; Phadia Laboratory Systems) were performed in both groups. RESULT: The rosacea patients had significantly more radiological evidence of CRS than the patients without rosacea [19 (67.9%) vs. 4 (20%), p = 0.003]. The median IgE concentration was similar in both groups (225.4 vs. 223.1 kU/l). Nine rosacea patients (32.1%) without radiological evidence of CRS did not have a significantly different median concentration of IgE compared with those who had radiological evidence of CRS (190.5 vs. 111.5 kU/l, p = 0.859). Erythematotelangiectatic severity was significantly associated with CRS (p = 0.038). Serum IgE did not correlate with the severity of the facial condition. CONCLUSION: Patients with rosacea and CRS manifested severe erythematotelangiectatic rosacea. There was enough evidence to suggest an association between rosacea and CRS. Clinical and radiological assessments of the paranasal sinuses are recommended. S. Karger AG 2014-11 2014-07-24 /pmc/articles/PMC5586923/ /pubmed/25060422 http://dx.doi.org/10.1159/000364905 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
spellingShingle Original Paper
Al-Balbeesi, Amal O.
Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study
title Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study
title_full Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study
title_fullStr Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study
title_full_unstemmed Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study
title_short Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study
title_sort rosacea and chronic rhinosinusitis: a case-controlled study
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586923/
https://www.ncbi.nlm.nih.gov/pubmed/25060422
http://dx.doi.org/10.1159/000364905
work_keys_str_mv AT albalbeesiamalo rosaceaandchronicrhinosinusitisacasecontrolledstudy