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Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study
OBJECTIVE: To determine the relationship between rosacea, chronic rhinosinusitis (CRS), and the clinical presentation of rosacea. SUBJECTS AND METHOD: Twenty-eight female Saudi patients diagnosed with rosacea at the Dermatology Clinic, King Khalid University Hospital, King Saud University, Riyadh, S...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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S. Karger AG
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586923/ https://www.ncbi.nlm.nih.gov/pubmed/25060422 http://dx.doi.org/10.1159/000364905 |
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author | Al-Balbeesi, Amal O. |
author_facet | Al-Balbeesi, Amal O. |
author_sort | Al-Balbeesi, Amal O. |
collection | PubMed |
description | OBJECTIVE: To determine the relationship between rosacea, chronic rhinosinusitis (CRS), and the clinical presentation of rosacea. SUBJECTS AND METHOD: Twenty-eight female Saudi patients diagnosed with rosacea at the Dermatology Clinic, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia, between September 2011 and September 2012 and 20 age- and sex-matched control patients were included in the study. Paranasal sinus X-rays and assessments of the serum concentration of IgE (ImmunoCAP test; Phadia Laboratory Systems) were performed in both groups. RESULT: The rosacea patients had significantly more radiological evidence of CRS than the patients without rosacea [19 (67.9%) vs. 4 (20%), p = 0.003]. The median IgE concentration was similar in both groups (225.4 vs. 223.1 kU/l). Nine rosacea patients (32.1%) without radiological evidence of CRS did not have a significantly different median concentration of IgE compared with those who had radiological evidence of CRS (190.5 vs. 111.5 kU/l, p = 0.859). Erythematotelangiectatic severity was significantly associated with CRS (p = 0.038). Serum IgE did not correlate with the severity of the facial condition. CONCLUSION: Patients with rosacea and CRS manifested severe erythematotelangiectatic rosacea. There was enough evidence to suggest an association between rosacea and CRS. Clinical and radiological assessments of the paranasal sinuses are recommended. |
format | Online Article Text |
id | pubmed-5586923 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-55869232017-11-01 Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study Al-Balbeesi, Amal O. Med Princ Pract Original Paper OBJECTIVE: To determine the relationship between rosacea, chronic rhinosinusitis (CRS), and the clinical presentation of rosacea. SUBJECTS AND METHOD: Twenty-eight female Saudi patients diagnosed with rosacea at the Dermatology Clinic, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia, between September 2011 and September 2012 and 20 age- and sex-matched control patients were included in the study. Paranasal sinus X-rays and assessments of the serum concentration of IgE (ImmunoCAP test; Phadia Laboratory Systems) were performed in both groups. RESULT: The rosacea patients had significantly more radiological evidence of CRS than the patients without rosacea [19 (67.9%) vs. 4 (20%), p = 0.003]. The median IgE concentration was similar in both groups (225.4 vs. 223.1 kU/l). Nine rosacea patients (32.1%) without radiological evidence of CRS did not have a significantly different median concentration of IgE compared with those who had radiological evidence of CRS (190.5 vs. 111.5 kU/l, p = 0.859). Erythematotelangiectatic severity was significantly associated with CRS (p = 0.038). Serum IgE did not correlate with the severity of the facial condition. CONCLUSION: Patients with rosacea and CRS manifested severe erythematotelangiectatic rosacea. There was enough evidence to suggest an association between rosacea and CRS. Clinical and radiological assessments of the paranasal sinuses are recommended. S. Karger AG 2014-11 2014-07-24 /pmc/articles/PMC5586923/ /pubmed/25060422 http://dx.doi.org/10.1159/000364905 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only. |
spellingShingle | Original Paper Al-Balbeesi, Amal O. Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study |
title | Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study |
title_full | Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study |
title_fullStr | Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study |
title_full_unstemmed | Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study |
title_short | Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study |
title_sort | rosacea and chronic rhinosinusitis: a case-controlled study |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586923/ https://www.ncbi.nlm.nih.gov/pubmed/25060422 http://dx.doi.org/10.1159/000364905 |
work_keys_str_mv | AT albalbeesiamalo rosaceaandchronicrhinosinusitisacasecontrolledstudy |