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Pegylated-interferon plus ribavirin treatment does not alter the prevalence of resistance-associated substitutions to direct-acting antivirals in HCV genotype 1a patients

BACKGROUND: Direct-acting antiviral (DAA) resistance-associated substitutions (RASs) can jeopardize the effectiveness of DAAs in patients with hepatitis C virus (HCV). The selection pressure by pegylated-interferon (Peg-IFN) plus ribavirin (P/R) treatment may enhance HCV genome variation. However, w...

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Detalles Bibliográficos
Autores principales:	Chen, Zhi-wei, Pang, Xi-chen, Li, Zhao, Ren, Hong, Hu, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587017/ https://www.ncbi.nlm.nih.gov/pubmed/28919791 http://dx.doi.org/10.2147/IDR.S145362

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