RecA filament maintains structural integrity using ATP-driven internal dynamics

At the core of homologous DNA repair, RecA catalyzes the strand exchange reaction. This process is initiated by a RecA loading protein, which nucleates clusters of RecA proteins on single-stranded DNA. Each cluster grows to cover the single-stranded DNA but may leave 1- to 2-nucleotide (nt) gaps bet...

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Detalles Bibliográficos
Autores principales: Kim, Sung Hyun, Ahn, TakKyoon, Cui, Tao Ju, Chauhan, Sweeny, Sung, Jaeyoung, Joo, Chirlmin, Kim, Doseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587095/
https://www.ncbi.nlm.nih.gov/pubmed/28913424
http://dx.doi.org/10.1126/sciadv.1700676

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