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Curvature and Rho activation differentially control the alignment of cells and stress fibers
In vivo, cells respond to a host of physical cues ranging from substrate stiffness to the organization of micro- and nanoscale fibrous networks. We show that macroscale substrates with radii of curvature from tens to hundreds of micrometers influence cell alignment. In a model system of fibroblasts,...
Autores principales: | Bade, Nathan D., Kamien, Randall D., Assoian, Richard K., Stebe, Kathleen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587136/ https://www.ncbi.nlm.nih.gov/pubmed/28913421 http://dx.doi.org/10.1126/sciadv.1700150 |
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