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Silencing of interferon regulatory factor gene 6 in melanoma

BACKGROUND: Methylation of a CpG island (CGI; a dense cluster of CpGs) located in the 5' region of a gene suppresses transcription of that gene. Interferon regulatory factor 6 (IRF6) is associated with the expression of interferon, which is used as an effective adjuvant therapy for melanoma, an...

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Detalles Bibliográficos
Autores principales:	Nobeyama, Yoshimasa, Nakagawa, Hidemi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587289/ https://www.ncbi.nlm.nih.gov/pubmed/28877249 http://dx.doi.org/10.1371/journal.pone.0184444

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