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Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population

INTRODUCTION ­­­Acute pericarditis is the most commonly encountered manifestation of pericardial disease (incidence: 0.2 percent to 0.5 percent in hospitalized patients). However, data regarding manifestations, workup, and the management of acute pericarditis in the African American population is la...

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Autores principales: Awan, Ahmad, Tiruneh, Fasil, Wessly, Priscilla, Khan, Akbar, Iftikhar, Hasan, Barned, Sydney, Larbi, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587407/
https://www.ncbi.nlm.nih.gov/pubmed/28924519
http://dx.doi.org/10.7759/cureus.1431
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author Awan, Ahmad
Tiruneh, Fasil
Wessly, Priscilla
Khan, Akbar
Iftikhar, Hasan
Barned, Sydney
Larbi, Daniel
author_facet Awan, Ahmad
Tiruneh, Fasil
Wessly, Priscilla
Khan, Akbar
Iftikhar, Hasan
Barned, Sydney
Larbi, Daniel
author_sort Awan, Ahmad
collection PubMed
description INTRODUCTION ­­­Acute pericarditis is the most commonly encountered manifestation of pericardial disease (incidence: 0.2 percent to 0.5 percent in hospitalized patients). However, data regarding manifestations, workup, and the management of acute pericarditis in the African American population is lacking. This study aims to collect and analyze more clinical data related to acute pericarditis in this understudied population. METHODOLOGY We conducted a retrospective chart review of all patients managed for acute pericarditis at a university hospital serving a predominantly African American population. A total of 78 charts were reviewed during the period of study from January 2011 to July 2016. Out of these, nine charts were excluded due to poor data. We descriptively analyzed data regarding presenting symptoms, underlying etiologies, co-morbidities, investigation results, management strategies, and prognoses. RESULTS We found an equal number of males and females in our study population. The most common comorbid conditions were hypertension, chronic kidney disease, and diabetes mellitus (in order of incidence). The most common presentation of symptomatic pericarditis consisted of chest pain, dyspnea, tachycardia, and tachypnea. Electrocardiogram (EKG) findings included diffuse ST elevation (15 percent) and sinus tachycardia (41 percent). Leukocytosis was seen in 15 percent of the patients. The most common etiology noted in our patient population was idiopathic and was treated with NSAIDS. CONCLUSION As compared to other populations, the incidence of uremic pericarditis and pericarditis secondary to cardiac etiologies is slightly higher in the African American population; however, the clinical presentation, examination and laboratory findings, as well as investigations, are remarkably similar. 
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spelling pubmed-55874072017-09-18 Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population Awan, Ahmad Tiruneh, Fasil Wessly, Priscilla Khan, Akbar Iftikhar, Hasan Barned, Sydney Larbi, Daniel Cureus Infectious Disease INTRODUCTION ­­­Acute pericarditis is the most commonly encountered manifestation of pericardial disease (incidence: 0.2 percent to 0.5 percent in hospitalized patients). However, data regarding manifestations, workup, and the management of acute pericarditis in the African American population is lacking. This study aims to collect and analyze more clinical data related to acute pericarditis in this understudied population. METHODOLOGY We conducted a retrospective chart review of all patients managed for acute pericarditis at a university hospital serving a predominantly African American population. A total of 78 charts were reviewed during the period of study from January 2011 to July 2016. Out of these, nine charts were excluded due to poor data. We descriptively analyzed data regarding presenting symptoms, underlying etiologies, co-morbidities, investigation results, management strategies, and prognoses. RESULTS We found an equal number of males and females in our study population. The most common comorbid conditions were hypertension, chronic kidney disease, and diabetes mellitus (in order of incidence). The most common presentation of symptomatic pericarditis consisted of chest pain, dyspnea, tachycardia, and tachypnea. Electrocardiogram (EKG) findings included diffuse ST elevation (15 percent) and sinus tachycardia (41 percent). Leukocytosis was seen in 15 percent of the patients. The most common etiology noted in our patient population was idiopathic and was treated with NSAIDS. CONCLUSION As compared to other populations, the incidence of uremic pericarditis and pericarditis secondary to cardiac etiologies is slightly higher in the African American population; however, the clinical presentation, examination and laboratory findings, as well as investigations, are remarkably similar.  Cureus 2017-07-06 /pmc/articles/PMC5587407/ /pubmed/28924519 http://dx.doi.org/10.7759/cureus.1431 Text en Copyright © 2017, Awan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Infectious Disease
Awan, Ahmad
Tiruneh, Fasil
Wessly, Priscilla
Khan, Akbar
Iftikhar, Hasan
Barned, Sydney
Larbi, Daniel
Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population
title Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population
title_full Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population
title_fullStr Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population
title_full_unstemmed Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population
title_short Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population
title_sort acute pericarditis: descriptive study and etiology determination in a predominantly african american population
topic Infectious Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587407/
https://www.ncbi.nlm.nih.gov/pubmed/28924519
http://dx.doi.org/10.7759/cureus.1431
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