α7 nicotinic acetylcholine receptor signaling modulates the inflammatory phenotype of fetal brain microglia: first evidence of interference by iron homeostasis

Neuroinflammation in utero may result in life-long neurological disabilities. Microglia play a pivotal role, but the mechanisms are poorly understood. No early postnatal treatment strategies exist to enhance neuroprotective potential of microglia. We hypothesized that agonism on α7 nicotinic acetylc...

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Detalles Bibliográficos
Autores principales: Cortes, M., Cao, M., Liu, H. L., Moore, C. S., Durosier, L. D., Burns, P., Fecteau, G., Desrochers, A., Barreiro, L. B., Antel, J. P., Frasch, M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587535/
https://www.ncbi.nlm.nih.gov/pubmed/28878260
http://dx.doi.org/10.1038/s41598-017-09439-z

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