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Hypoxia-inducible factor 1 alpha promotes cancer stem cells-like properties in human ovarian cancer cells by upregulating SIRT1 expression

Ovarian cancer have a poor overall survival rate in patients, and late disease presentation and chemoresistance are the main factors that lead to the mortality of ovarian cancer. Cancer stem cells (CSCs), a small subpopulation of cancer cells, have been associated with resistance to chemo- and radio...

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Detalles Bibliográficos
Autores principales:	Qin, Jie, Liu, Yan, Lu, Yongkui, Liu, Meiling, Li, Manli, Li, Juan, Wu, Lijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587562/ https://www.ncbi.nlm.nih.gov/pubmed/28878214 http://dx.doi.org/10.1038/s41598-017-09244-8

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