Germline Mutations in Cancer Predisposition Genes are Frequent in Sporadic Sarcomas

Associations of sarcoma with inherited cancer syndromes implicate genetic predisposition in sarcoma development. However, due to the apparently sporadic nature of sarcomas, little attention has been paid to the role genetic susceptibility in sporadic sarcoma. To address this, we performed targeted-g...

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Detalles Bibliográficos
Autores principales: Chan, Sock Hoai, Lim, Weng Khong, Ishak, Nur Diana Binte, Li, Shao-Tzu, Goh, Wei Lin, Tan, Gek San, Lim, Kiat Hon, Teo, Melissa, Young, Cedric Ng Chuan, Malik, Simeen, Tan, Mann Hong, Teh, Jonathan Yi Hui, Chin, Francis Kuok Choon, Kesavan, Sittampalam, Selvarajan, Sathiyamoorthy, Tan, Patrick, Teh, Bin Tean, Soo, Khee Chee, Farid, Mohamad, Quek, Richard, Ngeow, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587568/
https://www.ncbi.nlm.nih.gov/pubmed/28878254
http://dx.doi.org/10.1038/s41598-017-10333-x

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