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Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation
Joint modeling of a number of phenotypes using multivariate methods has often been neglected in genome-wide association studies and if used, replication has not been sought. Modern omics technologies allow characterization of functional phenomena using a large number of related phenotype measures, w...
Autores principales: | Shen, Xia, Klarić, Lucija, Sharapov, Sodbo, Mangino, Massimo, Ning, Zheng, Wu, Di, Trbojević-Akmačić, Irena, Pučić-Baković, Maja, Rudan, Igor, Polašek, Ozren, Hayward, Caroline, Spector, Timothy D., Wilson, James F., Lauc, Gordan, Aulchenko, Yurii S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587582/ https://www.ncbi.nlm.nih.gov/pubmed/28878392 http://dx.doi.org/10.1038/s41467-017-00453-3 |
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