The activation of α(2)-adrenergic receptor in the spinal cord lowers sepsis-induced mortality

The effect of clonidine administered intrathecally (i.t.) on the mortality and the blood glucose level induced by sepsis was examined in mice. To produce sepsis, the mixture of D-galactosamine (GaLN; 0.6 g/10 ml)/lipopolysaccharide (LPS; 27 µg/27 µl) was treated intraperitoneally (i.p.). The i.t. pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Sung-Su, Park, Soo-Hyun, Lee, Jae-Ryung, Jung, Jun-Sub, Suh, Hong-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587600/
https://www.ncbi.nlm.nih.gov/pubmed/28883754
http://dx.doi.org/10.4196/kjpp.2017.21.5.495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587600/
https://www.ncbi.nlm.nih.gov/pubmed/28883754
http://dx.doi.org/10.4196/kjpp.2017.21.5.495

Ejemplares similares