Persistent microglial activation and synaptic loss with behavioral abnormalities in mouse offspring exposed to CASPR2-antibodies in utero

Gestational transfer of maternal antibodies against fetal neuronal proteins may be relevant to some neurodevelopmental disorders, but until recently there were no proteins identified. We recently reported a fivefold increase in CASPR2-antibodies in mid-gestation sera from mothers of children with in...

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Detalles Bibliográficos
Autores principales: Coutinho, Ester, Menassa, David A., Jacobson, Leslie, West, Steven J., Domingos, Joana, Moloney, Teresa C., Lang, Bethan, Harrison, Paul J., Bennett, David L. H., Bannerman, David, Vincent, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587616/
https://www.ncbi.nlm.nih.gov/pubmed/28755208
http://dx.doi.org/10.1007/s00401-017-1751-5

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