APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism

Oral squamous cell carcinoma is a prominent cancer worldwide, particularly in Taiwan. By integrating omics analyses in 50 matched samples, we uncover in Taiwanese patients a predominant mutation signature associated with cytidine deaminase APOBEC, which correlates with the upregulation of APOBEC3A e...

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Detalles Bibliográficos
Autores principales: Chen, Ting-Wen, Lee, Chi-Ching, Liu, Hsuan, Wu, Chi-Sheng, Pickering, Curtis R., Huang, Po-Jung, Wang, Jing, Chang, Ian Yi-Feng, Yeh, Yuan-Ming, Chen, Chih-De, Li, Hsin-Pai, Luo, Ji-Dung, Tan, Bertrand Chin-Ming, Chan, Timothy En Haw, Hsueh, Chuen, Chu, Lichieh Julie, Chen, Yi-Ting, Zhang, Bing, Yang, Chia-Yu, Wu, Chih-Ching, Hsu, Chia-Wei, See, Lai-Chu, Tang, Petrus, Yu, Jau-Song, Liao, Wei-Chao, Chiang, Wei-Fan, Rodriguez, Henry, Myers, Jeffrey N., Chang, Kai-Ping, Chang, Yu-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587710/
https://www.ncbi.nlm.nih.gov/pubmed/28878238
http://dx.doi.org/10.1038/s41467-017-00493-9

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