A new mass spectrometry-based method for the quantification of histones in plasma from septic shock patients

The aim of this study was to develop a novel method to detect circulating histones H3 and H2B in plasma based on multiple reaction monitoring targeted mass spectrometry and a multiple reaction monitoring approach (MRM-MS) for its clinical application in critical bacteriaemic septic shock patients. P...

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Detalles Bibliográficos
Autores principales: García-Giménez, J. L., Romá-Mateo, C., Carbonell, N., Palacios, L., Peiró-Chova, L., García-López, E., García-Simón, M., Lahuerta, R., Gimenez-Garzó, C., Berenguer-Pascual, E., Mora, M. I., Valero, M. L., Alpízar, A., Corrales, F. J., Blanquer, J., Pallardó, F. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587716/
https://www.ncbi.nlm.nih.gov/pubmed/28878320
http://dx.doi.org/10.1038/s41598-017-10830-z

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