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Rate-limiting steps in transcription dictate sensitivity to variability in cellular components
Cell-to-cell variability in cellular components generates cell-to-cell diversity in RNA and protein production dynamics. As these components are inherited, this should also cause lineage-to-lineage variability in these dynamics. We conjectured that these effects on transcription are promoter initiat...
Autores principales: | Mäkelä, Jarno, Kandavalli, Vinodh, Ribeiro, Andre S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587725/ https://www.ncbi.nlm.nih.gov/pubmed/28878283 http://dx.doi.org/10.1038/s41598-017-11257-2 |
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