Regulatory dynamics of 11p13 suggest a role for EHF in modifying CF lung disease severity

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause cystic fibrosis (CF), but are not good predictors of lung phenotype. Genome-wide association studies (GWAS) previously identified additional genomic sites associated with CF lung disease severity. One of these, at...

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Detalles Bibliográficos
Autores principales: Stolzenburg, Lindsay R., Yang, Rui, Kerschner, Jenny L., Fossum, Sara, Xu, Matthew, Hoffmann, Andrew, Lamar, Kay-Marie, Ghosh, Sujana, Wachtel, Sarah, Leir, Shih-Hsing, Harris, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587731/
https://www.ncbi.nlm.nih.gov/pubmed/28549169
http://dx.doi.org/10.1093/nar/gkx482

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