Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells

Chromatin reorganization is necessary for pluripotent stem cells, including embryonic stem cells (ESCs), to acquire lineage potential. However, it remains unclear how ESCs maintain their characteristic chromatin state for appropriate gene expression upon differentiation. Here, we demonstrate that ch...

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Detalles Bibliográficos
Autores principales: Semba, Yuichiro, Harada, Akihito, Maehara, Kazumitsu, Oki, Shinya, Meno, Chikara, Ueda, Jun, Yamagata, Kazuo, Suzuki, Atsushi, Onimaru, Mitsuho, Nogami, Jumpei, Okada, Seiji, Akashi, Koichi, Ohkawa, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587750/
https://www.ncbi.nlm.nih.gov/pubmed/28549158
http://dx.doi.org/10.1093/nar/gkx475

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