Cargando…

Hyper-O-GlcNAcylation induces cisplatin resistance via regulation of p53 and c-Myc in human lung carcinoma

Aberrant metabolism in hexosamine biosynthetic pathway (HBP) has been observed in several cancers, affecting cellular signaling and tumor progression. However, the role of O-GlcNAcylation, a post-translational modification through HBP flux, in apoptosis remains unclear. Here, we found that hyper-O-G...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luanpitpong, Sudjit, Angsutararux, Paweorn, Samart, Parinya, Chanthra, Nawin, Chanvorachote, Pithi, Issaragrisil, Surapol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587763/ https://www.ncbi.nlm.nih.gov/pubmed/28878262 http://dx.doi.org/10.1038/s41598-017-10886-x

Ejemplares similares

O-GlcNAcylation homeostasis controlled by calcium influx channels regulates multiple myeloma dissemination
por: Samart, Parinya, et al.
Publicado: (2021)

Metabolic sensor O‐GlcNAcylation regulates megakaryopoiesis and thrombopoiesis through c‐Myc stabilization and integrin perturbation
por: Luanpitpong, Sudjit, et al.
Publicado: (2021)

A novel TRPM7/O-GlcNAc axis mediates tumour cell motility and metastasis by stabilising c-Myc and caveolin-1 in lung carcinoma
por: Luanpitpong, Sudjit, et al.
Publicado: (2020)

Chemotherapy-Induced Cardiotoxicity: Overview of the Roles of Oxidative Stress
por: Angsutararux, Paweorn, et al.
Publicado: (2015)

Metabolic sensor O-GlcNAcylation regulates erythroid differentiation and globin production via BCL11A
por: Luanpitpong, Sudjit, et al.
Publicado: (2022)

Correction: Metabolic sensor O-GlcNAcylation regulates erythroid differentiation and globin production via BCL11A
por: Luanpitpong, Sudjit, et al.
Publicado: (2022)

SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma
por: Luanpitpong, Sudjit, et al.
Publicado: (2015)

A novel E-cadherin/SOX9 axis regulates cancer stem cells in multiple myeloma by activating Akt and MAPK pathways
por: Samart, Parinya, et al.
Publicado: (2022)

Musashi-2 in cancer-associated fibroblasts promotes non-small cell lung cancer metastasis through paracrine IL-6-driven epithelial-mesenchymal transition
por: Samart, Parinya, et al.
Publicado: (2023)

Bcl-2 Family Members Bcl-xL and Bax Cooperatively Contribute to Bortezomib Resistance in Mantle Cell Lymphoma
por: Luanpitpong, Sudjit, et al.
Publicado: (2022)

Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction
por: Zhang, Jie, et al.
Publicado: (2021)

GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation
por: Dorfmueller, Helge C., et al.
Publicado: (2009)

Mass Spectrometry for O-GlcNAcylation
por: Yin, Ruoting, et al.
Publicado: (2021)

The role of O-GlcNAcylation in development
por: Czajewski, Ignacy, et al.
Publicado: (2023)

Hyper-O-GlcNAcylation promotes epithelial-mesenchymal transition in endometrial cancer cells
por: Jaskiewicz, Nicole Morin, et al.
Publicado: (2019)

O-GlcNAcylation: The Sweet Side of the Cancer
por: de Queiroz, Rafaela Muniz, et al.
Publicado: (2014)

O-GlcNAcylation and Metabolic Reprograming in Cancer
por: Jóźwiak, Paweł, et al.
Publicado: (2014)

O-GlcNAcylation Is Essential for Autophagy in Cardiomyocytes
por: Yu, Houzhi, et al.
Publicado: (2020)

Editorial: O-GlcNAcylation: Expanding the Frontiers
por: Issad, Tarik, et al.
Publicado: (2019)

Role and Function of O-GlcNAcylation in Cancer
por: Lee, Jii Bum, et al.
Publicado: (2021)

O-GlcNAcylation Prediction: An Unattained Objective
por: Mauri, Theo, et al.
Publicado: (2021)

O-GlcNAcylation in health and neurodegenerative diseases
por: Lee, Byeong Eun, et al.
Publicado: (2021)

Targeting O-GlcNAcylation in ischemic stroke
por: Li, Xuan, et al.
Publicado: (2022)

O-GlcNAcylation in Renal (Patho)Physiology
por: Silva-Aguiar, Rodrigo P., et al.
Publicado: (2022)

Emerging field: O-GlcNAcylation in ferroptosis
por: Zhang, Hongshuo, et al.
Publicado: (2023)

Increased O-GlcNAcylation of c-Myc Promotes Pre-B Cell Proliferation
por: Lee, Da Hee, et al.
Publicado: (2020)

Generation of a synthetic GlcNAcylated nucleosome reveals regulation of stability by H2A-Thr101 GlcNAcylation
por: Lercher, Lukas, et al.
Publicado: (2015)

Regulation of O-GlcNAcylation on endothelial nitric oxide synthase by glucose deprivation and identification of its O-GlcNAcylation sites
por: He, An, et al.
Publicado: (2020)

Pancreatic β-cell hyper-O-GlcNAcylation leads to impaired glucose homeostasis in vivo
por: Jo, Seokwon, et al.
Publicado: (2022)

Induced Pluripotent Stem Cells as a Tool for Modeling Hematologic Disorders and as a Potential Source for Cell-Based Therapies
por: Pratumkaew, Ponthip, et al.
Publicado: (2021)

SLC35B4 Stabilizes c-MYC Protein by O-GlcNAcylation in HCC
por: Jiang, Tao, et al.
Publicado: (2022)

Suppressive Regulation of KSHV RTA with O-GlcNAcylation
por: Ko, Ying-Chieh, et al.
Publicado: (2012)

O-GlcNAcylation: A New Cancer Hallmark?
por: Fardini, Yann, et al.
Publicado: (2013)

Identification of O-GlcNAcylated proteins in Plasmodium falciparum
por: Kupferschmid, Mattis, et al.
Publicado: (2017)

Effects of hypo-O-GlcNAcylation on Drosophila development
por: Mariappa, Daniel, et al.
Publicado: (2018)

The role of O‐GlcNAcylation in immunity against infections
por: Quik, Marjolein, et al.
Publicado: (2020)

Functional Analysis of O-GlcNAcylation in Cancer Metastasis
por: Wu, Donglu, et al.
Publicado: (2020)

O-GlcNAcylation and its role in the immune system
por: Chang, Yi-Hsuan, et al.
Publicado: (2020)

The Role of O-GlcNAcylation in Immune Cell Activation
por: Qiang, Amy, et al.
Publicado: (2021)

Chemistry-Assisted Proteomic Profiling of O-GlcNAcylation
por: Zhu, Qiang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d1tts2u4n8in3jov7eu745ldmm